張益銍 (Yi-Chih Chang)
姓名 張益銍 (Yi-Chih Chang)
職稱 專任副教授
學歷 國立中興大學 獸醫學系 博士
國立陽明大學 醫學生物技術暨檢驗學系所 碩士
中國醫藥學院 醫事技術學系 學士
元培醫專 檢驗科
經歷 亞洲大學 醫技系 系主任 111年12月~
亞洲大學 生物科技系 助理教授
中國醫藥大學 醫學檢驗暨生物技術學系 助理教授
中台科技大學 醫學檢驗生物技術學系 助理教授
中國醫藥大學 醫學檢驗暨生物技術學系 講師
中國醫藥學院 醫事技術學系 助教
社團法人台中市長期照顧發展協會 學術顧問
社團法人南投縣長期照顧發展協會 學術顧問
台中科技大學、逢甲大學、修平科技大學等校教師申訴評議委員會委員
 
電子郵件
分機 04-23323456#1926
辦公室/研究室 M610/HB27
研究領域 臨床微生物學、細胞診斷及組織病理學技術、臨床鏡檢學、毒物檢驗學
專長 分子細菌學、臨床細菌學、臨床檢驗學、血液壆含實驗、生物學、醫學檢驗概論、微生物學含實驗、免疫學、分子生物學、腫瘤生物學、應用微生物學、生物醫學技術概論、醫學倫理、遺傳學
年度 論文名稱
2021 Jan-Gowth Chang、田霓(Ni Tien)、張益銍(Yi-Chih Chang)、林孟亮(Meng-Liang Lin)、陳世順(Shih-Shun Chen)*, Oxidative Stress-Induced Unscheduled CDK1-Cyclin B1 Activity Impairs ER-Mitochondria-Mediated Bioenergetic Metabolism, Cells, vol.10 pp.1280-, 2021
2021 Sien-Sing Yang、Yi-Hsun Chen、Jui-Ting Hu、Ching-Feng Chiu、 Shao-Wen Hung、張益銍(Yi-Chih Chang)、Chien-Chao Chiu、 Hsiao-Li Chuang( Hsiao-Li Chuang)*, Aldehyde Dehydrogenase Mutation Exacerbated High-Fat-Diet-Induced Nonalcoholic Fatty Liver Disease with Gut Microbiota Remodeling in Male Mice, BIOLOGY OF THE NEONATE, vol.10 no.8 pp.737-751, 2021
2021 莊曉莉(Hsiao-Li Chuang)、張益銍(Yi-Chih Chang)、黃奕婷(Yi-Ting Huang)、廖君旺(Jiunn-Wang Liao)、高培玲(Pei-Ling Kao)、陳逸飛(Yi-Fei Chen)、林秉誼(Bin-Yin Lin)、林奕洛(Yi-Lo Lin)、陳德勛(Ter-Hsin Chen)、王裕智(Yu-Chih Wang)*, Establishment and Characterization of Feline Mammary Tumor Patient-Derived Xenograft Model, Animals, vol.11 pp.2380-, 2021
2019 張益銍(Yi-Chih Chang)、莊曉莉(Hsiao-Li Chuang3,)、Ji-Hang Yin、Jiunn-Wang Liao、陳德勛(Ter-Hsin Chen)、王裕智(Yu-Chih Wang)*, Significance of sphingosine kinase 1 expression in feline mammary tumors, BMC Veterinary Research, vol.15 no.1 pp.155-162, 2019
2019 張益銍(Yi-Chih Chang), Significance of sphingosine kinase 1 expressuon in feline mammary tumors., SOLAR ENERGY MATERIALS AND SOLAR CELLS, 2019
2017 張益銍(Yi-Chih Chang), Relationship of the CreBC two-component regulatory system and inner membrane protein CreD with swimming motility in Stenotrophomonas maltophilia, PLoS One, 2017
2017 張益銍(Yi-Chih Chang), Tubacin, an HDAC6 Selective Inhibitor, Reduces the Replication of the Japanese Encephalitis Virus via the Decrease of Viral RNA Synthesis, PLoS One, 2017
2017 張益銍(Yi-Chih Chang), TLR2 and interleukin-10 are involved in Bacteroides fragilis-mediated prevention of DSS-induced colitis in gnotobiotic mice., PLoS One, 2017
2017 張益銍(Yi-Chih Chang), Differences in Genetic Background Contribute to Pseudomonas Exotoxin A-Induced Hepatotoxicity in Rats, JOURNAL OF VENOMOUS ANIMALS AND TOXINS INCLUDING TROPICAL DISEASES, 2017
2017 張益銍(Yi-Chih Chang), Class 1 integrons and plasmid-mediated multiple resistance genes of the Campylobacter species from pediatric patient of a university hospital in Taiwan, Gut Pathogens, 2017
2016 張益銍(Yi-Chih Chang), Comparison of the surface roughness of gypsum models constructed using various impression materials and gypsum products, Journal of Dental Sciences, 2016
2016 張益銍(Yi-Chih Chang), Benzyl butyl phthalate promotes breast cancer stem cell expansion via SPHK1/S1P/S1PR3 signaling, OncoTargets and Therapy, 2016
2013 張益銍(Yi-Chih Chang), Association between hypertensive disorders during pregnancy and end-stage renal disease: a population-based study, CANADIAN MEDICAL ASSOCIATION JOURNAL, 2013
2012 張益銍(Yi-Chih Chang), Bacteremia in hemodialysis and peritoneal dialysis patients, ANNALS OF INTERNAL MEDICINE, 2012
2012 張益銍(Yi-Chih Chang), Risks, subtypes, and hospitalization costs of stroke among patients with systemic lupus erythematosus: a retrospective cohort study in Taiwan, SCANDINAVIAN JOURNAL OF RHEUMATOLOGY, 2012
2012 張益銍(Yi-Chih Chang), Antiviral Activity of Isatis indigotica Extract and Its Derived Indirubin against Japanese Encephalitis Virus, Evidence-based Complementary and Alternative Medicine, 2012
2012 張益銍(Yi-Chih Chang), Ameliorative Effects of Scopoletin from Crossostephium chinensis against Inflammation Pain and Its Mechanisms in Mice. Evid Based Complement Alternat Med, Evidence-based Complementary and Alternative Medicine, 2012
2012 張益銍(Yi-Chih Chang), Real-time PCR analysis of the intestinal microbiotas in peritoneal dialysis patients, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2012
2011 張益銍(Yi-Chih Chang), SmQnrR, a DeoR-type transcriptional regulator, negatively regulates the expression of Smqnr and SmtcrA in Stenotrophomonas maltophilia, JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2011
2011 張益銍(Yi-Chih Chang), Transmission of Salmonella between swine farms by the housefly (Musca domestica), JOURNAL OF FOOD PROTECTION, 2011
2009 張益銍(Yi-Chih Chang), Analysis of ciprofloxacin-resistant Salmonella strains from swine, chicken, and their carcasses in Taiwan and detection of parC resistance mutations by a mismatch amplification mutation assay PCR, JOURNAL OF FOOD PROTECTION, 2009
2009 張益銍(Yi-Chih Chang), Characterization of the charge variants of L2 beta-lactamase in Stenotrophomonas maltophilia, JOURNAL OF MEDICAL MICROBIOLOGY, 2009
2006 張益銍(Yi-Chih Chang), Construction and characterization of nisin-controlled expression vectors for use in Lactobacillus reuteri, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2006
2006 張益銍(Yi-Chih Chang), Rapid detection and identification of clinically important bacteria by high-resolution melting analysis after broad-range ribosomal RNA real-time PCR, CLINICAL CHEMISTRY, 2006
年度 書名
2021 吳俊忠(Jiunn-Jong Wu)、張益銍(Yi-Chih Chang), 臨床微生物學-細菌與黴菌學(第八版), 五南圖書公司, Oct. 2021
2019 吳俊忠(Wu, Jiunn-Jong)、吳雪霞(Wu, Hsueh-Hsia)、周以正(Chou, Yii-Cheng)、周如文(Chou, Ru-wen)、胡文熙(Ho, Wen-si S)、洪貴香(Hong, Gui-xiang)、孫培倫(Sun, Pei-lun)、張長泉(Chang, Chang-Tsung)、張益銍(Yi-Chih Chang), 臨床微生物學-細菌及黴菌學, 五南出版社出版。, Oct. 2019
發表日期 論文名稱
2022.05 楊子賢(Zi-Xian Yang)、王廷瑋( Ting-Wei Wang)、陳世順( Shih-Shun Chen)、鄧志敦(Chih-Tun Teng)、蔡相德(Hsiang-Te Tsai)、張益銍(Yi-Chih Chang)、田霓(Ni Tien), The antimicrobial potentiality of antipsychotics (sulpiride and amisulpride) against important standard strains , 2022 Joint Biotechnology Conference of China Medical University and Asia University, May. 2022, Taiwan, Taichung, China Medical University
2022.05 王廷瑋(Ting-Wei Wang)、林慧怡(Hui-Yi Lin)、陳世順( Shih-Shun Chen)、鄧志敦(Chih-Tun Teng)、張益銍(Yi-Chih Chang)、田霓(Ni Tien), Analysis of the antibacterial activity of curcumin and magnolol against Gram, positive and Gram-negative bacterium - 2022 Joint Biotechnology Conference of China Medical University and Asia University, May. 2022, Taiwan, Taichung, China Medical University
2022.05 陳立恩(Li-En Chen)、林秉穎(Bing-Ing Lin)、陳羿妃(Yi-Fei Chen)、蘇郁銘(Yu-Ming Su)、王裕智(Yu-Chih Wang)、張益銍(Yi-Chih Chang), Research on the creation of tumor exosomes as anticancer drug carriers , 2022 Joint Biotechnology Conference of China Medical University and Asia University, May. 2022, Taiwan, Taichung, China Medical University
2021.11 蘇郁銘(Yu-Ming Su)、莊宗原(Tzong-Yuan Juang)、林冠語(Kuan-Yu Lin)、林君黛(Jun-Dai Lin)、鄧志敦(Chih-Tun Teng)、許玉龍( Yu-Lung Hsu)、陳世順(Shih-Shun Chen)、張益銍(Yi-Chih Chang)、田霓(Ni Tien), Antibacterial activity of carbon nanodots derived from natural plants among Gram, positive and Gram-negative strains - The Thirteenth First General Meeting and Academic Presentation, Nov. 2021, University Hospital International Conference Center
2020.05 謝程豐(Cheng-Feng Hsieh)、田霓(Ni Tien)、許玉龍(Yu-Lung Hsu)、鄧志敦(Chih-Tun Teng)、林冠語(Kuan-Yu Lin)、林君黛(Lin, Jun-Dai)、張益銍(Yi-Chih Chang), Analysis the antimicrobial susceptibility of Clostridium difficile from university hospital at the western area of Taiwan. , 2020 Joint Biotechnology Conference of China Medical University and Asia University, May. 2020, Taiwan, Taichung,China Medical University
2019.05 許楷翔( Kai-Hsiang Hsu)、張益銍(Yi-Chih Chang), Detection of tetracycline resistance genes in Campylobacter species isolates from human, chicken and swine specimens. , 2019 Joint Biotechnology Conference of Asia University and China Medical University., May. 2019, Taiwan/Taichung/Asia University
2019.05 方詰愷(Jie-Kai Fang)、張益銍(Yi-Chih Chang), Analysis the adhesive virulence genes (cadF, flaA and racR genes) in Campylobacter species isolates from human and animal specimens. , 2019 Joint Biotechnology Conference of China Medical University and Asia University., May. 2019, Taiwan/Taichung/Asia University
2019.05 陳雅玲(Chen, Ya-ling)、林君黛(Lin, Jun-Dai)、陳麗麗(Chen, Li-Li)、吳珮瑜(Wu, Ju-yu)、張益銍(Yi-Chih Chang)、林冠語(Kuan-Yu Lin), 國中青少女原發性痛經與中醫體質相關性研究 , 2019玉山研討會., May. 2019, 台灣,台中,中台科技大學
2019.04 鄧志敦(Chih-Tun Teng)、張昱偉(Yu-Wei Chang)、賴小婷(Hsiao-Ting Lai)、林貞(Chen Lin)、陳昱衡(Yu-Heng Chen)、張益銍(Yi-Chih Chang), 11th Asia-Pacific Forum of Medical Laboratory Sciences 2019., Apr. 2019, Taiwan, Taichung, Chung Shan Medical University, Taichung
2019.04 鄧志敦(Chih-Tun Teng), An Experience Sharing of Optimizing Laboratory Management Process , Using SharePoint into Management Department Process as an Example. - 11th Asia-Pacific Forum of Medical Laboratory Sciences, Apr. 2019, Chung Shan Medical University, Taichung
2018.11 興仁傑(Ren-Jay Shing)、張益銍(Yi-Chih Chang), Analysis of erythromycin reisitance genes in Campylobacter species isolates from human, chicken and swine specimens , 107年度醫檢學會年度大會學術研討會, Nov. 2018, 台灣台北台大醫院國際會議中心
2018.11 林妍伶(Yan-Ling Lin)、張益銍(Yi-Chih Chang), 偵測在人類、雞和豬隻檢體中彎曲桿菌侵襲毒力基因的分析表現(Detection the invasion virulence genes (ciaB, iam, pldA, and virBll genes) in Campylobacter species isolates from human, chicken and swine specimens) , 台灣微生物學會第二十二屆第三次會員大會暨學術研討會, Nov. 2018, 台灣台北 台灣大學醫學院101,102講堂
2018.11 Hsiang-Te Tsai、張益銍(Yi-Chih Chang), 台灣西部地區豬隻腸道乳酸桿菌耐酸鹼特性分析(Analysis the acid tolerance and bile salts hydrolysis of Lactobacillus species from swine intestinal specimens at the western area of Taiwan) , 台灣微生物學會第二十二屆第三次會員大會暨學術研討會, Nov. 2018, 台灣台北台灣大學醫學院
2018.05 羅凱騰(Kai-Teng Lo)、張益銍(Yi-Chih Chang), Detection the major virulence genes (cytolethal distending toxin genes) in Campylobacter species isolates from human, chicken and swine specimens , 2018年中國醫藥大學暨亞洲大學生物科技研討會, May. 2018, 台灣台中中國醫藥大學B1國際會議廳
2018.05 林昭岑(Chao-Tsen Lin)、張益銍(Yi-Chih Chang)、鄧志敦(Chih-Tun Teng), 13. The antimicrobial susceptibility test of Stapylococcus aureus and beta, hemolytic streptococci by VITEK 2 system at east area of Taiwan - 2018年中國醫藥大學暨亞洲大學生物科技研討會, May. 2018, 台灣台中中國醫藥大學B1國際會議廳
2018.05 林昭岑(Chao-Tsen Lin)、張益銍(Yi-Chih Chang)、鄧志敦( Chih-Tun Teng), 14. Analysis the antimicrobial susceptibility test of Gram, Negative Bacilli by VITEK 2 system in Taitung Christian Hospital, Taitung - 2018年中國醫藥大學暨亞洲大學生物科技研討會, May. 2018, 台灣台中中國醫藥大學B1國際會議廳
2016.11 吳柏寬(Bo-Kuan Wu)、張益銍(Yi-Chih Chang), Molecular characterization of Campylobacter species isolated from pediatric gastroenteritis patients at central area of Taiwan , 台灣醫檢雜誌 (105年度年會大會), Nov. 2016, 台灣台北國際會議中心
2016.11 陳弘翰(Hong-Han Chen)、張益銍(Yi-Chih Chang), Analysis the patterm of gene cassette arrays in class I integron from clinical Acinetobacter baumanni isolates at central area of Taiwan , 台灣醫檢雜誌 (105年度年會大會), Nov. 2016, 台灣台北國際會議中心
2016.03 田霓(Ni Tien)、張益銍(Yi-Chih Chang), Antimicrobial activity of synthetic analogues (Hsu, 48 drug) against the emergence of antimicrobial resistance MRSA and coagulase-negative Staphylococci - 第九屆中國醫藥大學暨亞洲大學生物科技研討會, Mar. 2016, 台灣台中中國醫藥大學立夫教學大樓B1國際會議廳
2016.03 萬宗函(Tsung-Han Wan)、張益銍(Yi-Chih Chang), Antimicrobial susceptibility of Hsu, 48 drug against the emergence of antimicrobial resistance beta-hemolytic streptococci in clinical isolates - 第九屆中國醫藥大學暨亞洲大學生物科技研討會, Mar. 2016, 台灣台中中國醫藥大學立夫教學大樓B1國際會議廳
2016.03 蔡相德(Hsiang-Te Tsai)、張益銍(Yi-Chih Chang), Analysis of class I Integron from multiple drug resistance Acinetobacter baumanni in clinical isolates , 第九屆中國醫藥大學暨亞洲大學生物科技研討會, Mar. 2016, 中國醫藥大學立夫教學大樓B1國際會議廳
2015.10 田霓(Ni Tien)、張益銍(Yi-Chih Chang), Antimicrobial activity of Hsu, 48 drug (a new nordihydroguaiaretic acid derivative) in clinical pathogens - 台灣微生物學會第二十一屆第三次台灣微生物學會年會暨會員大會, Oct. 2015, 台灣台北國際會議中心
2014.10 曾煥鴻(Huan-Hung Tseng)、張益銍(Yi-Chih Chang)、吳怡瑩(YI-YING Wu), NC, 8 inhibits RANK ligand induced osteoclast differentiation from Monocyte/ Macrophages Lineage precursor cell - 2014年中華民國免疫學會會員大會暨學術演講會, Oct. 2014, 台灣台灣大學醫學院一樓102、103、104講堂
2013.11 王怡寬, Antimicrobial activity of vanillin against lactic acid bacteria isolated from indigenous children feces at the western area of Taiwan. , 「益生菌及代謝物之多重應用」學術與產業應用研討會暨台灣乳酸菌協會第五屆第二次會員大會, Nov. 2013, 台灣大學凝態物理館2F國際會議廳
2013.11 王怡寬, Antimicrobial susceptibility of vanillin against several Lactobacillus species isolated from swine guts at the western area of Taiwan. , 「益生菌及代謝物之多重應用」學術與產業應用研討會暨台灣乳酸菌協會第五屆第二次會員大會, Nov. 2013, 台灣大學凝態物理館2F國際會議廳
2013.08 王怡寬, Antimicrobial activity of vanillin to the emergence of antimicrobial resistance pathogens in clinical isolates. , 第18屆細菌學研討會, Aug. 2013, 惠蓀實驗林場
2013.03 鄧宛蓉, 中草藥木通誘發單核球/巨噬細胞的前驅細胞分化成為蝕骨細胞 , 第六屆亞洲大學與中國醫藥大學兩校合作學術研討會, Mar. 2013, 亞洲大學行政大樓一樓哈佛講堂、管理大樓地下一樓
2010.03 林怡婷, Lactobacillus can suppress the apoptosis that caused by Helicobacter pylori infection , 第三屆亞洲大學及中國醫藥大學生物技術聯合研討會, Mar. 2010, 亞洲大學
2009.02 許振婷, 14. Upregulation of CCL20 and Recruitment of CCR6 Gastric Infiltrating Lymphocytes in Helicobacter pylori Gastritis , 97年度中國醫藥大學P3-4研究學習群之推廣, 2009研究學習群校級研究成果發表會, Feb. 2009, 日月潭教師會館
2009.02 許振婷, 幽門螺旋桿菌胃炎病人會增加趨化激素CCL20的表現量並召集CCR6+胃浸潤T細胞 , 2009研究學習群日月潭校級研究成果發表會, Feb. 2009, 日月潭
2008.12 張益銍(Yi-Chih Chang), Distribution of tet genes and antimicrobial susceptibility of several Lactobacillus species isolated from swine guts at the western area of Taiwan. , 發酵乳的無可取代價值」學術研討會暨台灣乳酸菌協會第三屆第一次會員大會, Dec. 2008, 弘光科技大學生活應用大樓國際會議廳
2008.06 T-H. Chen, Investigation of Salmonella Infection in Household and Stray Dogs of Central Taiwan , The 108th General Meeting of the American Society for Microbiology, Jun. 2008, Boston, MA, USA.
2008.06 張益銍(Yi-Chih Chang), The AmpR Protein Regulates the L1 β, Lactamase Expression in Stenotrophomonas maltophilia - The 108th General Meeting of the American Society for Microbiology, Jun. 2008, Boston, MA, USA.
2008.06 Y-C. Wang, Antimicrobial Resistance and Genetic Relatedness among Salmonella Schwarzengrund from Slaughtering Broiler and Human. , The 108th General Meeting of the American Society for Microbiology, Jun. 2008, Boston, MA, USA.
2007.12 張益銍(Yi-Chih Chang), Antimicrobial activity of cultural secretions from probiotics Lactobacillus acidophilus against some antibiotic, resistant pathogens isolated from pediatric populations. - 台灣微生物學會第四十週年慶會員大會學術研討會, Dec. 2007, 台北市臺大醫院國際會議中心
2007.07 Yu-Chih Wang, Rapid detection of fluoroquinolone, resistant Salmonella by Multiplex Allele specific PCR - 第三屆沙門氏菌暨其他細菌人畜共通疾病研討會, Jul. 2007, 台中市 , 中興大學獸醫學院
2006.11 張益銍(Yi-Chih Chang), Distribution of tetracycline resistant genes in lactic acid bacteria isolated from human feces and swine guts in Taiwan , 台灣乳酸菌協會2006年年度大會暨學術研討會, Nov. 2006, 台北市 , 台灣大學凝態科學暨物理學館國際會議廳(二樓204室)
2006.11 張益銍(Yi-Chih Chang), Characterization of anti, bacterial and cholesterol-lowering function for Enterococcus faecium 57a-1, 58a-1, and 63b-2 - 台灣乳酸菌協會2006年年度大會暨學術研討會, Nov. 2006, 台北市 , 台灣大學凝態科學暨物理學館國際會議廳(二樓204室)
計畫名稱 參與人 計畫期間
貓乳腺瘤外泌體SPHK1與肝轉移前微環境建立 ((110-2313-B-005-047-)) 王裕智(Yu-Chih Wang) 2021.08 ~ 2022.07
獎項名稱 頒獎單位
Antimicrobial susceptibility of cefoxitin and penicillin G against the emergence of clinical Clostridium difficile isolates Taiwan Lactic Acid Bacteria Association.
課程類別 課程代碼 課程名稱 年度
大學日間部 TM300026B 寄生蟲學實驗 111
大學日間部 TM300031A 臨床微生物學 111
大學日間部 TM300032A 臨床微生物學實驗 111
大學日間部 TM300032B 臨床微生物學實驗 111
大學日間部 TM300033A 臨床鏡檢學 111
大學日間部 TM300034A 臨床鏡檢學實驗 111
大學日間部 TM300034B 臨床鏡檢學實驗 111
研究所碩士班 TM200011A 碩士論文 111
大學日間部 TM300025A 寄生蟲學 111
大學日間部 TM300026A 寄生蟲學實驗 111
大學日間部 GOG00447A 動物與生活-4 111
年度 名稱 全部作者
109 Prevalence of antimicrobial susceptibility tests and antibiotic resistance genes in Clostridium difficile isolated from a university hospital medical laboratory bacterial repository in central Taiwan 謝程豐
109 Analysis major virulence genes and regulatory genes of Clostridium difficile from university hospital at the western area of Taiwan 盧易辰