张益铚 (Yi-Chih Chang)
姓名 张益铚 (Yi-Chih Chang)
职称 专任副教授
学历 国立中兴大学 兽医学系 博士
国立阳明大学 医学生物技术暨检验学系所 硕士
中国医药学院 医事技术学系 学士
元培医专 检验科
经历 亚洲大学 医技系 系主任 111年12月~
亚洲大学 生物科技系 助理教授
中国医药大学 医学检验暨生物技术学系 助理教授
中台科技大学 医学检验生物技术学系 助理教授
中国医药大学 医学检验暨生物技术学系 讲师
中国医药学院 医事技术学系 助教
社团法人台中市长期照顾发展协会 学术顾问
社团法人南投县长期照顾发展协会 学术顾问
台中科技大学、逢甲大学、修平科技大学等校教师申诉评议委员会委员
 
电子邮件
分机 04-23323456#1926
办公室/研究室 M610/HB27
研究领域 临床微生物学、细胞诊断及组织病理学技术、临床镜检学、毒物检验学
专长 分子细菌学、临床细菌学、临床检验学、血液壆含实验、生物学、医学检验概论、微生物学含实验、免疫学、分子生物学、肿瘤生物学、应用微生物学、生物医学技术概论、医学伦理、遗传学
年度 论文名称
2021 Jan-Gowth Chang、田霓(Ni Tien)、张益铚(Yi-Chih Chang)、林孟亮(Meng-Liang Lin)、陈世顺(Shih-Shun Chen)*, Oxidative Stress-Induced Unscheduled CDK1-Cyclin B1 Activity Impairs ER-Mitochondria-Mediated Bioenergetic Metabolism, Cells, vol.10 pp.1280-, 2021
2021 Sien-Sing Yang、Yi-Hsun Chen、Jui-Ting Hu、Ching-Feng Chiu、 Shao-Wen Hung、张益铚(Yi-Chih Chang)、Chien-Chao Chiu、 Hsiao-Li Chuang( Hsiao-Li Chuang)*, Aldehyde Dehydrogenase Mutation Exacerbated High-Fat-Diet-Induced Nonalcoholic Fatty Liver Disease with Gut Microbiota Remodeling in Male Mice, BIOLOGY OF THE NEONATE, vol.10 no.8 pp.737-751, 2021
2021 庄晓莉(Hsiao-Li Chuang)、张益铚(Yi-Chih Chang)、黄奕婷(Yi-Ting Huang)、廖君旺(Jiunn-Wang Liao)、高培玲(Pei-Ling Kao)、陈逸飞(Yi-Fei Chen)、林秉谊(Bin-Yin Lin)、林奕洛(Yi-Lo Lin)、陈德勋(Ter-Hsin Chen)、王裕智(Yu-Chih Wang)*, Establishment and Characterization of Feline Mammary Tumor Patient-Derived Xenograft Model, Animals, vol.11 pp.2380-, 2021
2019 张益铚(Yi-Chih Chang)、庄晓莉(Hsiao-Li Chuang3,)、Ji-Hang Yin、Jiunn-Wang Liao、陈德勋(Ter-Hsin Chen)、王裕智(Yu-Chih Wang)*, Significance of sphingosine kinase 1 expression in feline mammary tumors, BMC Veterinary Research, vol.15 no.1 pp.155-162, 2019
2019 张益铚(Yi-Chih Chang), Significance of sphingosine kinase 1 expressuon in feline mammary tumors., SOLAR ENERGY MATERIALS AND SOLAR CELLS, 2019
2017 张益铚(Yi-Chih Chang), Relationship of the CreBC two-component regulatory system and inner membrane protein CreD with swimming motility in Stenotrophomonas maltophilia, PLoS One, 2017
2017 张益铚(Yi-Chih Chang), Tubacin, an HDAC6 Selective Inhibitor, Reduces the Replication of the Japanese Encephalitis Virus via the Decrease of Viral RNA Synthesis, PLoS One, 2017
2017 张益铚(Yi-Chih Chang), TLR2 and interleukin-10 are involved in Bacteroides fragilis-mediated prevention of DSS-induced colitis in gnotobiotic mice., PLoS One, 2017
2017 张益铚(Yi-Chih Chang), Differences in Genetic Background Contribute to Pseudomonas Exotoxin A-Induced Hepatotoxicity in Rats, JOURNAL OF VENOMOUS ANIMALS AND TOXINS INCLUDING TROPICAL DISEASES, 2017
2017 张益铚(Yi-Chih Chang), Class 1 integrons and plasmid-mediated multiple resistance genes of the Campylobacter species from pediatric patient of a university hospital in Taiwan, Gut Pathogens, 2017
2016 张益铚(Yi-Chih Chang), Comparison of the surface roughness of gypsum models constructed using various impression materials and gypsum products, Journal of Dental Sciences, 2016
2016 张益铚(Yi-Chih Chang), Benzyl butyl phthalate promotes breast cancer stem cell expansion via SPHK1/S1P/S1PR3 signaling, OncoTargets and Therapy, 2016
2013 张益铚(Yi-Chih Chang), Association between hypertensive disorders during pregnancy and end-stage renal disease: a population-based study, CANADIAN MEDICAL ASSOCIATION JOURNAL, 2013
2012 张益铚(Yi-Chih Chang), Bacteremia in hemodialysis and peritoneal dialysis patients, ANNALS OF INTERNAL MEDICINE, 2012
2012 张益铚(Yi-Chih Chang), Risks, subtypes, and hospitalization costs of stroke among patients with systemic lupus erythematosus: a retrospective cohort study in Taiwan, SCANDINAVIAN JOURNAL OF RHEUMATOLOGY, 2012
2012 张益铚(Yi-Chih Chang), Antiviral Activity of Isatis indigotica Extract and Its Derived Indirubin against Japanese Encephalitis Virus, Evidence-based Complementary and Alternative Medicine, 2012
2012 张益铚(Yi-Chih Chang), Ameliorative Effects of Scopoletin from Crossostephium chinensis against Inflammation Pain and Its Mechanisms in Mice. Evid Based Complement Alternat Med, Evidence-based Complementary and Alternative Medicine, 2012
2012 张益铚(Yi-Chih Chang), Real-time PCR analysis of the intestinal microbiotas in peritoneal dialysis patients, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2012
2011 张益铚(Yi-Chih Chang), SmQnrR, a DeoR-type transcriptional regulator, negatively regulates the expression of Smqnr and SmtcrA in Stenotrophomonas maltophilia, JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2011
2011 张益铚(Yi-Chih Chang), Transmission of Salmonella between swine farms by the housefly (Musca domestica), JOURNAL OF FOOD PROTECTION, 2011
2009 张益铚(Yi-Chih Chang), Analysis of ciprofloxacin-resistant Salmonella strains from swine, chicken, and their carcasses in Taiwan and detection of parC resistance mutations by a mismatch amplification mutation assay PCR, JOURNAL OF FOOD PROTECTION, 2009
2009 张益铚(Yi-Chih Chang), Characterization of the charge variants of L2 beta-lactamase in Stenotrophomonas maltophilia, JOURNAL OF MEDICAL MICROBIOLOGY, 2009
2006 张益铚(Yi-Chih Chang), Construction and characterization of nisin-controlled expression vectors for use in Lactobacillus reuteri, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2006
2006 张益铚(Yi-Chih Chang), Rapid detection and identification of clinically important bacteria by high-resolution melting analysis after broad-range ribosomal RNA real-time PCR, CLINICAL CHEMISTRY, 2006
年度 书名
2021 吴俊忠(Jiunn-Jong Wu)、张益铚(Yi-Chih Chang), 临床微生物学-细菌与霉菌学(第八版), 五南图书公司, Oct. 2021
2019 吴俊忠(Wu, Jiunn-Jong)、吴雪霞(Wu, Hsueh-Hsia)、周以正(Chou, Yii-Cheng)、周如文(Chou, Ru-wen)、胡文熙(Ho, Wen-si S)、洪贵香(Hong, Gui-xiang)、孙培伦(Sun, Pei-lun)、张长泉(Chang, Chang-Tsung)、张益铚(Yi-Chih Chang), 临床微生物学-细菌及霉菌学, 五南出版社出版。, Oct. 2019
发表日期 论文名称
2022.05 杨子贤(Zi-Xian Yang)、王廷玮( Ting-Wei Wang)、陈世顺( Shih-Shun Chen)、邓志敦(Chih-Tun Teng)、蔡相德(Hsiang-Te Tsai)、张益铚(Yi-Chih Chang)、田霓(Ni Tien), The antimicrobial potentiality of antipsychotics (sulpiride and amisulpride) against important standard strains , 2022 Joint Biotechnology Conference of China Medical University and Asia University, May. 2022, Taiwan, Taichung, China Medical University
2022.05 王廷玮(Ting-Wei Wang)、林慧怡(Hui-Yi Lin)、陈世顺( Shih-Shun Chen)、邓志敦(Chih-Tun Teng)、张益铚(Yi-Chih Chang)、田霓(Ni Tien), Analysis of the antibacterial activity of curcumin and magnolol against Gram, positive and Gram-negative bacterium - 2022 Joint Biotechnology Conference of China Medical University and Asia University, May. 2022, Taiwan, Taichung, China Medical University
2022.05 陈立恩(Li-En Chen)、林秉颖(Bing-Ing Lin)、陈羿妃(Yi-Fei Chen)、苏郁铭(Yu-Ming Su)、王裕智(Yu-Chih Wang)、张益铚(Yi-Chih Chang), Research on the creation of tumor exosomes as anticancer drug carriers , 2022 Joint Biotechnology Conference of China Medical University and Asia University, May. 2022, Taiwan, Taichung, China Medical University
2021.11 苏郁铭(Yu-Ming Su)、庄宗原(Tzong-Yuan Juang)、林冠语(Kuan-Yu Lin)、林君黛(Jun-Dai Lin)、邓志敦(Chih-Tun Teng)、许玉龙( Yu-Lung Hsu)、陈世顺(Shih-Shun Chen)、张益铚(Yi-Chih Chang)、田霓(Ni Tien), Antibacterial activity of carbon nanodots derived from natural plants among Gram, positive and Gram-negative strains - The Thirteenth First General Meeting and Academic Presentation, Nov. 2021, University Hospital International Conference Center
2020.05 谢程丰(Cheng-Feng Hsieh)、田霓(Ni Tien)、许玉龙(Yu-Lung Hsu)、邓志敦(Chih-Tun Teng)、林冠语(Kuan-Yu Lin)、林君黛(Lin, Jun-Dai)、张益铚(Yi-Chih Chang), Analysis the antimicrobial susceptibility of Clostridium difficile from university hospital at the western area of Taiwan. , 2020 Joint Biotechnology Conference of China Medical University and Asia University, May. 2020, Taiwan, Taichung,China Medical University
2019.05 许楷翔( Kai-Hsiang Hsu)、张益铚(Yi-Chih Chang), Detection of tetracycline resistance genes in Campylobacter species isolates from human, chicken and swine specimens. , 2019 Joint Biotechnology Conference of Asia University and China Medical University., May. 2019, Taiwan/Taichung/Asia University
2019.05 方诘恺(Jie-Kai Fang)、张益铚(Yi-Chih Chang), Analysis the adhesive virulence genes (cadF, flaA and racR genes) in Campylobacter species isolates from human and animal specimens. , 2019 Joint Biotechnology Conference of China Medical University and Asia University., May. 2019, Taiwan/Taichung/Asia University
2019.05 陈雅玲(Chen, Ya-ling)、林君黛(Lin, Jun-Dai)、陈丽丽(Chen, Li-Li)、吴珮瑜(Wu, Ju-yu)、张益铚(Yi-Chih Chang)、林冠语(Kuan-Yu Lin), 国中青少女原发性痛经与中医体质相关性研究 , 2019玉山研讨会., May. 2019, 台湾,台中,中台科技大学
2019.04 邓志敦(Chih-Tun Teng)、张昱伟(Yu-Wei Chang)、赖小婷(Hsiao-Ting Lai)、林贞(Chen Lin)、陈昱衡(Yu-Heng Chen)、张益铚(Yi-Chih Chang), 11th Asia-Pacific Forum of Medical Laboratory Sciences 2019., Apr. 2019, Taiwan, Taichung, Chung Shan Medical University, Taichung
2019.04 邓志敦(Chih-Tun Teng), An Experience Sharing of Optimizing Laboratory Management Process , Using SharePoint into Management Department Process as an Example. - 11th Asia-Pacific Forum of Medical Laboratory Sciences, Apr. 2019, Chung Shan Medical University, Taichung
2018.11 兴仁杰(Ren-Jay Shing)、张益铚(Yi-Chih Chang), Analysis of erythromycin reisitance genes in Campylobacter species isolates from human, chicken and swine specimens , 107年度医检学会年度大会学术研讨会, Nov. 2018, 台湾台北台大医院国际会议中心
2018.11 林妍伶(Yan-Ling Lin)、张益铚(Yi-Chih Chang), 侦测在人类、鸡和猪只检体中弯曲杆菌侵袭毒力基因的分析表现(Detection the invasion virulence genes (ciaB, iam, pldA, and virBll genes) in Campylobacter species isolates from human, chicken and swine specimens) , 台湾微生物学会第二十二届第三次会员大会暨学术研讨会, Nov. 2018, 台湾台北 台湾大学医学院101,102讲堂
2018.11 Hsiang-Te Tsai、张益铚(Yi-Chih Chang), 台湾西部地区猪只肠道乳酸杆菌耐酸碱特性分析(Analysis the acid tolerance and bile salts hydrolysis of Lactobacillus species from swine intestinal specimens at the western area of Taiwan) , 台湾微生物学会第二十二届第三次会员大会暨学术研讨会, Nov. 2018, 台湾台北台湾大学医学院
2018.05 罗凯腾(Kai-Teng Lo)、张益铚(Yi-Chih Chang), Detection the major virulence genes (cytolethal distending toxin genes) in Campylobacter species isolates from human, chicken and swine specimens , 2018年中国医药大学暨亚洲大学生物科技研讨会, May. 2018, 台湾台中中国医药大学B1国际会议厅
2018.05 林昭岑(Chao-Tsen Lin)、张益铚(Yi-Chih Chang)、邓志敦(Chih-Tun Teng), 13. The antimicrobial susceptibility test of Stapylococcus aureus and beta, hemolytic streptococci by VITEK 2 system at east area of Taiwan - 2018年中国医药大学暨亚洲大学生物科技研讨会, May. 2018, 台湾台中中国医药大学B1国际会议厅
2018.05 林昭岑(Chao-Tsen Lin)、张益铚(Yi-Chih Chang)、邓志敦( Chih-Tun Teng), 14. Analysis the antimicrobial susceptibility test of Gram, Negative Bacilli by VITEK 2 system in Taitung Christian Hospital, Taitung - 2018年中国医药大学暨亚洲大学生物科技研讨会, May. 2018, 台湾台中中国医药大学B1国际会议厅
2016.11 吴柏宽(Bo-Kuan Wu)、张益铚(Yi-Chih Chang), Molecular characterization of Campylobacter species isolated from pediatric gastroenteritis patients at central area of Taiwan , 台湾医检杂志 (105年度年会大会), Nov. 2016, 台湾台北国际会议中心
2016.11 陈弘翰(Hong-Han Chen)、张益铚(Yi-Chih Chang), Analysis the patterm of gene cassette arrays in class I integron from clinical Acinetobacter baumanni isolates at central area of Taiwan , 台湾医检杂志 (105年度年会大会), Nov. 2016, 台湾台北国际会议中心
2016.03 田霓(Ni Tien)、张益铚(Yi-Chih Chang), Antimicrobial activity of synthetic analogues (Hsu, 48 drug) against the emergence of antimicrobial resistance MRSA and coagulase-negative Staphylococci - 第九届中国医药大学暨亚洲大学生物科技研讨会, Mar. 2016, 台湾台中中国医药大学立夫教学大楼B1国际会议厅
2016.03 万宗函(Tsung-Han Wan)、张益铚(Yi-Chih Chang), Antimicrobial susceptibility of Hsu, 48 drug against the emergence of antimicrobial resistance beta-hemolytic streptococci in clinical isolates - 第九届中国医药大学暨亚洲大学生物科技研讨会, Mar. 2016, 台湾台中中国医药大学立夫教学大楼B1国际会议厅
2016.03 蔡相德(Hsiang-Te Tsai)、张益铚(Yi-Chih Chang), Analysis of class I Integron from multiple drug resistance Acinetobacter baumanni in clinical isolates , 第九届中国医药大学暨亚洲大学生物科技研讨会, Mar. 2016, 中国医药大学立夫教学大楼B1国际会议厅
2015.10 田霓(Ni Tien)、张益铚(Yi-Chih Chang), Antimicrobial activity of Hsu, 48 drug (a new nordihydroguaiaretic acid derivative) in clinical pathogens - 台湾微生物学会第二十一届第三次台湾微生物学会年会暨会员大会, Oct. 2015, 台湾台北国际会议中心
2014.10 曾焕鸿(Huan-Hung Tseng)、张益铚(Yi-Chih Chang)、吴怡莹(YI-YING Wu), NC, 8 inhibits RANK ligand induced osteoclast differentiation from Monocyte/ Macrophages Lineage precursor cell - 2014年中华民国免疫学会会员大会暨学术演讲会, Oct. 2014, 台湾台湾大学医学院一楼102、103、104讲堂
2013.11 王怡宽, Antimicrobial activity of vanillin against lactic acid bacteria isolated from indigenous children feces at the western area of Taiwan. , 「益生菌及代谢物之多重应用」学术与产业应用研讨会暨台湾乳酸菌协会第五届第二次会员大会, Nov. 2013, 台湾大学凝态物理馆2F国际会议厅
2013.11 王怡宽, Antimicrobial susceptibility of vanillin against several Lactobacillus species isolated from swine guts at the western area of Taiwan. , 「益生菌及代谢物之多重应用」学术与产业应用研讨会暨台湾乳酸菌协会第五届第二次会员大会, Nov. 2013, 台湾大学凝态物理馆2F国际会议厅
2013.08 王怡宽, Antimicrobial activity of vanillin to the emergence of antimicrobial resistance pathogens in clinical isolates. , 第18届细菌学研讨会, Aug. 2013, 惠荪实验林场
2013.03 邓宛蓉, 中草药木通诱发单核球/巨噬细胞的前驱细胞分化成为蚀骨细胞 , 第六届亚洲大学与中国医药大学两校合作学术研讨会, Mar. 2013, 亚洲大学行政大楼一楼哈佛讲堂、管理大楼地下一楼
2010.03 林怡婷, Lactobacillus can suppress the apoptosis that caused by Helicobacter pylori infection , 第三届亚洲大学及中国医药大学生物技术联合研讨会, Mar. 2010, 亚洲大学
2009.02 许振婷, 14. Upregulation of CCL20 and Recruitment of CCR6 Gastric Infiltrating Lymphocytes in Helicobacter pylori Gastritis , 97年度中国医药大学P3-4研究学习群之推广, 2009研究学习群校级研究成果发表会, Feb. 2009, 日月潭教师会馆
2009.02 许振婷, 幽门螺旋杆菌胃炎病人会增加趋化激素CCL20的表现量并召集CCR6+胃浸润T细胞 , 2009研究学习群日月潭校级研究成果发表会, Feb. 2009, 日月潭
2008.12 张益铚(Yi-Chih Chang), Distribution of tet genes and antimicrobial susceptibility of several Lactobacillus species isolated from swine guts at the western area of Taiwan. , 发酵乳的无可取代价值」学术研讨会暨台湾乳酸菌协会第三届第一次会员大会, Dec. 2008, 弘光科技大学生活应用大楼国际会议厅
2008.06 T-H. Chen, Investigation of Salmonella Infection in Household and Stray Dogs of Central Taiwan , The 108th General Meeting of the American Society for Microbiology, Jun. 2008, Boston, MA, USA.
2008.06 张益铚(Yi-Chih Chang), The AmpR Protein Regulates the L1 β, Lactamase Expression in Stenotrophomonas maltophilia - The 108th General Meeting of the American Society for Microbiology, Jun. 2008, Boston, MA, USA.
2008.06 Y-C. Wang, Antimicrobial Resistance and Genetic Relatedness among Salmonella Schwarzengrund from Slaughtering Broiler and Human. , The 108th General Meeting of the American Society for Microbiology, Jun. 2008, Boston, MA, USA.
2007.12 张益铚(Yi-Chih Chang), Antimicrobial activity of cultural secretions from probiotics Lactobacillus acidophilus against some antibiotic, resistant pathogens isolated from pediatric populations. - 台湾微生物学会第四十周年庆会员大会学术研讨会, Dec. 2007, 台北市台大医院国际会议中心
2007.07 Yu-Chih Wang, Rapid detection of fluoroquinolone, resistant Salmonella by Multiplex Allele specific PCR - 第三届沙门氏菌暨其他细菌人畜共通疾病研讨会, Jul. 2007, 台中市 , 中兴大学兽医学院
2006.11 张益铚(Yi-Chih Chang), Distribution of tetracycline resistant genes in lactic acid bacteria isolated from human feces and swine guts in Taiwan , 台湾乳酸菌协会2006年年度大会暨学术研讨会, Nov. 2006, 台北市 , 台湾大学凝态科学暨物理学馆国际会议厅(二楼204室)
2006.11 张益铚(Yi-Chih Chang), Characterization of anti, bacterial and cholesterol-lowering function for Enterococcus faecium 57a-1, 58a-1, and 63b-2 - 台湾乳酸菌协会2006年年度大会暨学术研讨会, Nov. 2006, 台北市 , 台湾大学凝态科学暨物理学馆国际会议厅(二楼204室)
计画名称 参与人 计画期间
猫乳腺瘤外泌体SPHK1与肝转移前微环境建立 ((110-2313-B-005-047-)) 王裕智(Yu-Chih Wang) 2021.08 ~ 2022.07
奖项名称 颁奖单位
Antimicrobial susceptibility of cefoxitin and penicillin G against the emergence of clinical Clostridium difficile isolates Taiwan Lactic Acid Bacteria Association.
课程类别 课程代码 课程名称 年度
大学日间部 TM300026B 寄生虫学实验 111
大学日间部 TM300031A 临床微生物学 111
大学日间部 TM300032A 临床微生物学实验 111
大学日间部 TM300032B 临床微生物学实验 111
大学日间部 TM300033A 临床镜检学 111
大学日间部 TM300034A 临床镜检学实验 111
大学日间部 TM300034B 临床镜检学实验 111
研究所硕士班 TM200011A 硕士论文 111
大学日间部 TM300025A 寄生虫学 111
大学日间部 TM300026A 寄生虫学实验 111
大学日间部 GOG00447A 动物与生活-4 111
年度 名称 全部作者
109 Prevalence of antimicrobial susceptibility tests and antibiotic resistance genes in Clostridium difficile isolated from a university hospital medical laboratory bacterial repository in central Taiwan 谢程丰
109 Analysis major virulence genes and regulatory genes of Clostridium difficile from university hospital at the western area of Taiwan 卢易辰