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研究領域成果
近三年發表成果蔡政芳
Yu-Wen Wang, Bor-Ren Huang, Dah-Yuu Lu, Jin-Wun Chen, Vichuda Charoensaensuk, Liang-Yo Yang, Sheng-Wei Lai, Cheng-Fang Tsai* (通訊作者) and Wei-Lan Yeh (2024, Dec). Fenofibrate Inhibits LPS and Zymosan-induced Inflammatory Responses through Sonic Hedgehog in IMG Cells. Current Molecular Pharmacology, 17: e18761429317532
Chao-Wei Chen, Wei-Lan Yeh, Vichuda Charoensaensuk, Chingju Lin, Liang-Yo Yang, Mao-Kai Chen, Tong Yeh, Cheng-Fang Tsai* (通訊作者) and Dah-Yuu Lu (2024, Oct). Oral administration of osthole mitigates maladaptive behaviors through PPARα activation in mice subjected to repeated social defeat stress. Neurochemistry International,179:10587
Chao-Wei Chen, Wei-Lan Yeh, Vichuda Charoensaensuk, Chingju Lin, Liang-Yo Yang, Sheng-Yun Xie, Hsien-Yuan Lane, Chieh-Hsin Lin, Yu-Wen Wang, Cheng-Fang Tsai* (通訊作者) and Dah-Yuu Lu (2024, Aug). Ramelteon protects against social defeat stress-associated abnormal behaviors. Pharmacology Biochemistry and Behavior, 241: 173194
Vichuda Charoensaensuk, Wei-Lan Yeh, Bor-Ren Huang, Tsung-Che Hsu, Sheng-Yun Xie, Chao-Wei Chen, Yu-Wen Wang, Liang-Yo Yang, Cheng-Fang Tsai* (通訊作者) and Dah-Yuu Lu (2024, July). Repetitive Administration of Low-Dose Lipopolysaccharide Improves Repeated Social Defeat Stress-Induced Behavioral Abnormalities and Aberrant Immune Response. Journal of Neuroimmune Pharmacology, 19:38
Yen-Chang Chen, Jia-Hong Chen, Cheng-Fang Tsai, Chen-Yun Wu, Chen-Ni Chang,Chen-Teng Wu and Wei-Lan Yeh (2024, July). Protective effects of paeonol against cognitive impairment in lung diseases. Journal of Pharmacological Sciences, 155:101-112
Yen-Chang Chen, Jia-Hong Chen, Cheng-Fang Tsai, Chen-Teng Wu, Pei-Chun Chang, Wei-Lan Yeh (2024, Jan). Inhibition of tumor migration and invasion by fenofibrate via suppressing epithelial-mesenchymal transition in breast cancers, Toxicology and Applied Pharmacology, 483:116818
Cheng-Fang Tsai (第一作者),Yen-Chang Chen, Ya-Zhen Li , Chen-Teng Wu, Pei-Chun Chang and Wei-Lan Yeh (2023, Dec). Imperatorin ameliorates pulmonary fibrosis via GDF15 expression. Frontiers in Pharmacology, 14:1292137
Ching-Kai Shen, Bor-Ren Huang, Vichuda Charoensaensuk, Liang-Yo Yang, Cheng-Fang Tsai, Yu-Shu Liu, Sheng-Wei Lai, Dah-Yuu Lu, Wei-Lan Yeh, Chingju Lin (2023, Nov). Inhibitory Effects of Urolithins, Bioactive Gut Metabolites from Natural Polyphenols, against Glioblastoma Progression Nutrients. Nutrients, 15:4854 Ching-Kai Shen, Bor-Ren Huang, Vichuda Charoensaensuk, Liang-Yo Yang, Cheng-Fang Tsai, Yu-Shu Liu, Lu, Dah-Yuu, Yeh, Wei-Lan,
Chingju Lin (2023, Jul). Bradykinin B1 Receptor Affects Tumor-Associated Macrophage Activity and Glioblastoma Progression. Antioxidants, 12: 1533
Wei-Lan Yeh, Bor-Ren Huang, Guan-Wei Chen, Vichuda Charoensaensuk, Cheng-Fang Tsai, Liang-Yo Yang, Dah-Yuu Lu, Mao-Kai Chen, and Chingju Lin (2022, Dec). Role of Zerumbone, a Phytochemical Sesquiterpenoid from Zingiber zerumbet Smith, in Maintaining Macrophage Polarization and Redox Homeostasis. Nutrients, 14:5402
Yen-Chang Chen, Chen-Teng Wu, Jia-Hong Chen, Cheng-Fang Tsai, Chen-Yun Wu, Pei-Chun Chang, Wei-Lan Yeh (2022, Aug). Diltiazem inhibits breast cancer metastasis via mediating growth differentiation factor 15 and epithelial-mesenchymal transition. Oncogenesis, 11(1):48
Cheng-Fang Tsai* (第一作者及通訊作者), Guan-Wei Che, Yen-Chang Chen, Ching-Kai Shen, Dah-Yuu Lu, Liang-Yo Yang, Jia-Hong Chen and Wei-Lan Yeh* (2022, Jan). Regulatory Effects of Quercetin on M1/M2 Macrophage Polarization and Oxidative/Antioxidative Balance. Nutrients, 14:67.
Yen-Chang Chen, Yu-Kai Cheng, Jia-Hong Chen, Cheng-Fang Tsai, Tsung-Kai Wang , Chen-Yun Wu, Pei-Chun Chang, Wei-Lan Yeh (2022, Jan). Cardamonin attenuates phorbol 12-myristate 13-acetate-induced pulmonary inflammation in alveolar macrophages. Food and Chemical Toxicology, 159:112761
呂旭峯
NagPIBAF upregulation and OmpO downregulation compromise oxidative stress tolerance of Stenotrophomonas maltophilia. Yang TC, Wu SC, Yeh TY, Lu HF(第四作者), Lin YT, Li LH. BMC Microbiol. 2025 25(1):122.
Contribution of fepAsm, fciABC, sbaA, sbaBCDEF, and feoB to ferri-stenobactin acquisition in Stenotrophomonas maltophilia KJ. Ting-Yu Yeh, Hsu-Feng Lu(並列第一), Li-Hua Li, Yi-Tsung Lin, Tsuey-Ching Yang. BMC Microbiol. 2025 Feb 25;25(1):91.
Roles of the rpoEc-chrR-chrA operon in superoxide tolerance and β-lactam susceptibility of Stenotrophomonas maltophilia. Ren-Hsuan Ku, Hsu-Feng Lu(並列第一), Li-Hua Li, Ting-Yu Yeh, Yi-Tsung Lin, Tsuey-Ching Yang. Front Cell Infect Microbiol. 2025 Feb 4;15:1492008.
A sbiT-sbiRS-gloIo regulatory circuit is involved in oxidative stress tolerance of Stenotrophomonas maltophilia. Cheng-Mu Wu, Yi-Tzu Lee, Hsu-Feng Lu(第三作者), Yen-Ling Lin, Tsuey-Ching Yang. Journal of Microbiology, Immunology and Infection 2024 Oct;57(5):827-831.
First report of the chromosomal integration of carbapenemase gene blaIMP-19 in Acinetobacter baumannii AB322: the legacy of integron in phage-plasmid? Shih Y-L, Bregente CJB, Chen PK, Thuy TTD, Chen Y-C, Kuo H-Y, Lu H-F(第七作者), Kao C-Y. Microbiol Spectr. 2024 Jun 4;12(6):e0038224.
HemU and TonB1 contribute to hemin acquisition in Stenotrophomonas maltophilia. Chun-Hsing Liao, Hsu-Feng Lu(並列第一), Ching-Wei Yang, Ting-Yu Yeh, Yi-Tsung Lin, Tsuey-Ching Yang. Front Cell Infect Microbiol. 2024 Mar 26;14:1380976.
Characterization of the broad-spectrum antibacterial activity of bacteriocin-like inhibitory substance-producing probiotics isolated from fermented foods. Thuy TTD, Lu HF(並列第一), Bregente CJB, Huang FA, Tu PC, Kao CY. BMC Microbiol. 2024 Mar 11;24(1):85.
Allyl isothiocyanate induces DNA damage and inhibits DNA repair-associated proteins in a human gastric cancer cells in vitro. Yung-Luen Shih, Sheng-Yao Hsu, Kuang-Chi Lai, Fu-Shin Chueh(食保闕甫伈), Yuan-Li Huang, Chao-Lin Kuo, Yung-Liang Chen, Chiung-Ju Chen, Shu-Fen Peng, Wen-Wen Huang, Hsu-Feng Lu(聯絡作者). Environ Toxicol. 2024 Oct;39(10):1303-1314.
Modulatory role of SmeQ in SmeYZ efflux pump-involved functions in Stenotrophomonas maltophilia. Hu EW, Lu HF(第二作者), Lin YT, Yang TC, Li LH. J Antimicrob Chemother. J Antimicrob Chemother. 2024 Feb 1;79(2):383-390.
Implication of the σE regulon members OmpO and σN in the ΔompA299-356-mediated decrease of oxidative stress tolerance in Stenotrophomonas maltophilia. Ren-Hsuan Ku, Li-Hua Li, Yi-Fu Liu, En-Wei Hu, Yi-Tsung Lin, Hsu-Feng Lu(第六作者), and Tsuey-Ching Yang. Microbiol Spectr. 2023 Aug 17;11(4):e0108023.
Identification of a novel interaction site between the large hepatitis delta antigen and clathrin that regulates the assembly of genotype III hepatitis delta virus. Chiou WC, Lu HF(並列第一), Chen JC, Lai YH, Chang MF, Huang YL, Tien N, Huang C. Virol J. 2022 Oct 17;19(1):163.
Bisdemethoxycurcumin suppresses human brain glioblastoma multiforme GBM 8401 cell migration and invasion via affecting NF-κB and MMP-2 and MMP-9 signaling pathway in vitro. Chen CJ, Shang HS, Huang YL, Tien N, Chen YL, Hsu SY, Wu RS, Tang CL, Lien JC, Lee MH, Lu HF(聯絡作者), Hsia TC. Environ Toxicol. 2022 Oct;37(10):2388-2397.
Whole-genome-sequence-based characterization of an NDM-5-producing uropathogenic Escherichia coli EC1390. Thuy TTD, Lu HF(並列第一), Kuo PY, Lin WH, Lin TP, Lee YT, Duong TTT, Wang MC, Lee YH, Wen LL, Chen YC, Kao CY. BMC Microbiol. 2022 Jun 6;22(1):150.
FadACB and smeU1VWU2X Contribute to Oxidative Stress-Mediated Fluoroquinolone Resistance in Stenotrophomonas maltophilia. Li LH, Lu HF(並列第一), Liu YF, Lin YT, Yang TC. Antimicrob Agents Chemother. 2022 Apr 19;66(4):e0204321.
The fciTABC and feoABI systems contribute to ferric citrate acquisition in Stenotrophomonas maltophilia. Liao CH, Lu HF(並列第一), Huang HH, Chen Y, Li LH, Lin YT, Yang TC. J Biomed Sci. 2022 Apr 27;29(1):26.
Involvement of the hemP-hemA-smlt0796-smlt0797 Operon in Hemin Acquisition by Stenotrophomonas maltophilia. Shih YL, Wu CM, Lu HF(第三作者), Li LH, Lin YT, Yang TC. Microbiol Spectr. 2022 Jun 29;10(3):e0032122.
陳世順
Impact of DNA Ligase 1 Genotypes on Childhood Acute Lymphocytic Leukemia. Hsu PC, Chen CC, Tsai HW, Chang WS, Pei JS, Wang YC, Lin ML, He JL, Chen SS, Tsai CW, Bau DT. In Vivo. 2025 Jan-Feb; 39(1): 152–159.
Impacts of Matrix Metalloproteinase-2 Promoter Genotypes on Breast Cancer Risk. Hung CC, Tsai CL, Chin YT, Wang YC, Liu CH, Lin ML, Chen SS, He JL, Tsai JW, Su CH, Bau DT, Chang WS. Cancer Genomics & Proteomics. 21 (5) 502-510.
Naringin Induces ROS-Stimulated G1 Cell-Cycle Arrest and Apoptosis in Nasopharyngeal Carcinoma Cells. Chen CH, Tien CN, Yao CH, Chen SJ, Bau DT, Pandey S, Yang HL, Hseu YC, Chen SS (聯絡作者), Lin ML. Environmental Toxicology. 2024. 39(11):5059-5073.
Let-7g Upregulation Attenuated the KRAS–PI3K–Rac1–Akt Axis-Mediated Bioenergetic Functions. Hung KC, Tien N, Bau DT, Yao CH, Chen CH, Yang JL, Lin ML, Chen SS (聯絡作者). Cells. 2023, 12(18), 2313.
Ex Vivo Model to Evaluate the Antibacterial and Anti-Inflammatory Effects of Gelatin–Tricalcium Phosphate Composite Incorporated with Emodin and Lumbrokinase for Bone Regeneration. Wang WL, Hsu YM, Lin ML, Chen SS, Lai YH, Huang CH, Yao CH. Bioengineering (Basel). 2023 Aug; 10(8): 906.
陳宗祺
Jyotika, R. K., Harish, S.*, Karthikeyan, G., Kumar, K. K., Murugan, M., Jayakanthan, M., and Chen, T.-C. (第六作者) 2024. Molecular approaches for the management of papaya ringspot virus infecting papaya: a comprehensive review. Molecular Biology Reports 51:981. https://doi.org/10.1007/s11033-024-09920-9 SCI
Wang, G.-D., Lin, C.-C., and Chen, T.-C.* (通訊作者) 2024. Development of attenuated viruses for effective protection against pepper veinal mottle virus in tomato crops. Viruses 16(5):687. https://doi.org/10.3390/v16050687 SCI
Kang, Y.-C., Yeh, S.-D.*, and Chen, T.-C.* (通訊作者) 2024. Leucine 127 of cucurbit chlorotic yellows virus P22 is crucial for its RNA silencing suppression activity and pathogenicity. Phytopathology 114(4):813-822. https://doi.org/10.1094/PHYTO-07-23-0227-R SCI
Lin, C.-C., Lin, S.-S., and Chen, T.-C.* (通訊作者) 2022. Complete genome sequence of Amazon lily mosaic virus isolated from amaryllis (Hippeastrum hybridum Hort.). Archives of Virology 167(6):1495-1498. https://doi.org/10.1007/s00705-022-05449-z SCI
Chen, T.-C.* (第一作者及通訊作者), Lin, Y.-C., Lin, C.-C., Lin, Y.-X., and Chen, Y.-K. 2022. Rose virome analysis and identification of a novel ilarvirus in Taiwan. Viruses 14(11):2537. https://doi.org/10.3390/v14112537 SCI
Dong, Z.-X., Lin, C.-C., Chen, Y.-K., Chou, C.-C., and Chen, T.-C.* (通訊作者) 2022. Identification of an emerging cucumber virus in Taiwan using Oxford nanopore sequencing technology. Plant Methods 18(12):143. https://doi.org/10.1186/s13007-022-00976-x SCI
林玉鳳
Yu-Feng Lin, Hsueh-Chou Lai, Chen-Sheng Lin, Ping-Yi Hung, Ju-Ying Kan, Shih-Wen Shih-Wen, Chih-Hao Lu, Svetlana Petrova, Lidia A Baltina *, Cheng- Wen Lin * (2024, Dec). Discovery of potent Dengue virus NS2B-NS3 protease inhibitors among Glycyrrhizic acid conjugates with amino acids and dipeptides esters. Viruses, 2024, 16(12), 1926.
Yu-Jen Chang, Uyen Nguyen Phuong Le, Jia-Jun Liu, Sin-Rong Li, Shao-Ting Chao, Hsueh-Chou Lai, Yu-Feng Lin, Kai-Cheng Hsu, Chih-Hao Lu, Cheng-Wen Lin (2023, Aug). Combining virtual screening with cis-/trans-cleavage enzymatic assays effectively reveals broad-spectrum inhibitors that target the main proteases of SARS-CoV-2 and MERS-CoV. Antiviral Research, 2023 Aug:216:105653
Chih-Hao Lu, Chih-Chieh Chen, Chin-Sheng Yu, Yen-Yi Liu, Jia-Jun Liu, Sung- Tai Wei and Yu-Feng Lin* (2022, Sep). MIB2: metal ion-binding site prediction and modeling server. Bioinformatics, 38 (18), 4428–4429.
Yu-Feng Lin, Jia-Jun Liu, Yu-Jen Chang, Chin-Sheng Yu, Wei Yi, Hsien-Yuan Lane and Chih-Hao Lu (2022, Jan). Predicting Anticancer Drug Resistance Mediated by Mutations. Pharmaceuticals, 2022, 15, 136
