張清堯 (Ching-Yao Chang)
狀態 教授
姓名 張清堯 (Ching-Yao Chang)
電子郵件 cychang@asia.edu.tw
職稱 專任教授
分機 04-23323456#1863
辦公室/研究室 I421/H407
學歷 國立中興大學化學 博士
研究領域 普通化學、有機化學
授課領域 普通化學、普通化學實驗、有機化學、有機化學實驗
教師歷程檔案 https://research.asia.edu.tw/TchEportfolio/index_1/930100838
Office Hours 1111教師在校時_張清堯.老師
網站 http://mlsb.asia.edu.tw/files/13-1119-73640.php?Lang=zh-tw
專長 普通化學、有機化學
經歷
中州技術學院 通識教育中心
中台醫護技術學院
朝陽科技大學 應用化學系
年度 論文名稱
2021 Yu-An Hsu、張清堯(Ching-Yao Chang), Anti-Inflammatory Effects of Resveratrol on Human Retinal Pigment Cells and a Myopia Animal Model, CURRENT ISSUES IN MOLECULAR BIOLOGY, vol.43 pp.716-727, 2021
2021 Peng-Tai Tien、Chia-Hung Lin(Chia-Hung Lin)*、張清堯(Ching-Yao Chang), Diacerein Inhibits Myopia Progression through Lowering Inflammation in Retinal Pigment Epithelial Cell, MEDIATORS OF INFLAMMATION, vol.2021 no.6660640 pp.1-11, 2021
2020 張清堯(Ching-Yao Chang)、萬磊(Lei Wan)*, Amelioration of bleomycin-induced pulmonary fibrosis via TGF-β-induced Smad and non-Smad signaling pathways in galectin-9-deficient mice and fibroblast cells, JOURNAL OF BIOMEDICAL SCIENCE, vol.27 no.24 pp.1-9, 2020
2020 En-Shyh Lin、張清堯(Ching-Yao Chang)、萬磊(Lei Wan)*, Ablation of Galectin-12 Inhibits Atherosclerosis through Enhancement of M2 Macrophage Polarization, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol.21 no.15 pp.5511-5524, 2020
2020 Peng?Tai Tien、張清堯(Ching-Yao Chang), Perfluorooctanoic acid in indoor particulate matter triggers oxidative stress and inflammation in corneal and retinal cells, Scientific Reports, vol.1 no.10 pp.15702-15713, 2020
2019 Chang-Ching Wei、張清堯(Ching-Yao Chang)、萬磊*, PM2.5 and NOx exposure promote myopia: clinical evidence and experimental proof, ENVIRONMENTAL POLLUTION, vol.254 pp.113031-113038, 2019
2018 魏長菁(Chang-Ching Wei)、萬磊*、, Allergic Conjunctivitis-induced Retinal Inflammation Promotes Myopia Progression, EBioMedicine, 2018
2018 Chia-Wen Lo、萬磊*、, Allyl isothiocyanate ameliorates obesity by inhibiting galectin-12, MOLECULAR NUTRITION & FOOD RESEARCH, 2018
2018 Yu-An Hsu、張清堯(Ching-Yao Chang)、萬磊*, Galectin-12 is Involved in Corn Silk-Induced Anti-Adipogenesis and Anti-Obesity Effects, The American journal of Chinese medicine, vol.46 no.5 pp.1-19, 2018
2018 萬磊*、張清堯, The synergistic effects of orthokeratology and atropine in slowing the progression of myopia, Journal of clinical medicine, vol.7 no.9 pp.259-267, 2018
2017 Yung-Jen Kun、、萬磊*、、, Kawasaki disease increases the incidence of myopia, Biomed Research International, 2017
2016 Lin, H.-J.、萬磊*, Role of Chronic Inflammation in Myopia Progression: Clinical Evidence and Experimental Validation, EBioMedicine, vol.10 pp.269-281, 2016
2016 萬磊*、張清堯(Ching-Yao Chang), Galectin-12 enhances inflammation by promoting M1 polarization of macrophages and reduces insulin sensitivity in adipocytes, GLYCOBIOLOGY, vol.26 pp.732-744, 2016
2016 Lin, C.-H.、萬磊*, Cold-water extracts of Grifola frondosa and its purified active fraction inhibit hepatocellular carcinoma in vitro and in vivo, EXPERIMENTAL BIOLOGY AND MEDICINE, vol.241 no.13 pp.1374-1385, 2016
2016 Hsu, Yu-An、張清堯(Ching-Yao Chang)、萬磊*, The anti-proliferative effects of type I IFN involve STAT6-mediated regulation of SP1 and BCL6, CANCER LETTERS, vol.375 pp.303-312, 2016
2015 張清堯(Ching-Yao Chang)、萬磊*, MUTYH Gene Polymorphisms as Risk Factors for Rheumatoid Arthritis, BioMed Research International, vol.2015 pp.1-8, 2015
2015 張清堯(Ching-Yao Chang)、萬磊*, Flavones inhibit breast cancer proliferation through the Akt/FOXO3a signaling pathway, BMC CANCER, vol.15 no.958 pp.1-12, 2015
2014 張清堯(Ching-Yao Chang), Structurally well-characterized zinc complexes bearing iminebenzotriazole phenoxide ligands: Synthesis, photoluminescent properties and catalysis for carbon dioxide/epoxide coupling, Journal of Organometallic Chemistry, vol.754 pp.16-25, 2014
2014 張清堯(Ching-Yao Chang)*, An Efficient Synthesis of the C27-C45 Fragment of Lagunamide A, a Cyclodepsipeptide with Potent Cytotoxic and Antimalarial Properties, TETRAHEDRON-ASYMMETRY, vol.25 no.2 pp.187-192, 2014
2014 張清堯(Ching-Yao Chang)、萬磊(Lei Wan)*, [PDF] Association of Interleukin-16 Polymorphisms with Graves' Disease in a Taiwanese Population, CHINESE JOURNAL OF PHYSIOLOGY, vol.57 no.2 pp.69-75, 2014
2013 黃素華(Su-Hua Huang)、張清堯(Ching-Yao Chang), Baicalein, Ethyl Acetate, and Chloroform Extracts of Scutellaria baicalensis Inhibit the Neuraminidase Activity of Pandemic 2009 H1N1 and Seasonal Influenza A Viruses, Evidence-based Complementary and Alternative Medicine, vol.2013 pp.1-11, 2013
2013 張清堯(Ching-Yao Chang)、萬磊(Lei Wan)*, Genetic variation in NOS2A is associated with a sustained virological response to peginterferon plus ribavirin therapy for chronic hepatitis C in Taiwanese Chinese, JOURNAL OF MEDICAL VIROLOGY, vol.85 no.7 pp.1206-1214, 2013
2012 張清堯(Ching-Yao Chang), Determination of trace indium in urine after preconcentration with a chelating resin-packed minicolumn, JOURNAL OF SEPARATION SCIENCE, vol.35 no.7 pp.846-852, 2012
2012 張清堯(Ching-Yao Chang)、林振文(CHENG-WEN LIN), Rhein Induces Apoptosis in Human Breast Cancer Cells, Evidence-based Complementary and Alternative Medicine, vol.2012 pp.1-8, 2012
2011 賴淑玲(Shu Ling Lai), (4Z)-4-[(2,6-Diisopropylanilino)(phenyl)methylidene]- 3-methy-1-phenyl-1H-pyrazol-5(4H)-one, ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, vol.E67 pp.o324-, 2011
2011 張清堯(Ching-Yao Chang), Efficient synthesis of the C1-C9 fragment of 7,8-O-isopropylidene protected iriomoteolide 3a derivative, JOURNAL OF THE CHINESE CHEMICAL SOCIETY, vol.58 no.1 pp.31-34, 2011
2011 張清堯(Ching-Yao Chang), A Short and Efficient Synthesis of a Novel Diarylheptanoid Isolated from Pleuranthodium Racemigerum, JOURNAL OF THE CHINESE CHEMICAL SOCIETY, vol.58 no.3 pp.286-289, 2011
2010 張清堯(Ching-Yao Chang), BF3-promoted synthesis of diarylhexahydrobenzo[f]isoquinoline, ORGANIC LETTERS, vol.12 pp.1176-1179, 2010
2010 張清堯(Ching-Yao Chang), Solannm lyratum extract affected immune response in normal and leukemia murine animal in vivo, HUMAN & EXPERIMENTAL TOXICOLOGY, vol.29 no.1 pp.359-367, 2010
2010 張清堯(Ching-Yao Chang), BF3-promoted synthesis of spiroindenyl heterocycles, TETRAHEDRON LETTERS, vol.51 pp.3154-3158, 2010
2010 許成光(Cheng-Kuang Hsu)、王建國(Chien-Kuo Wang)、張清堯(Ching-Yao Chang), Solanum lyratum extract inhibits Helicobacter pylori-mediated apoptosis in human gastric epithelial cells, ANTICANCER RESEARCH, vol.30 pp.1189-1194, 2010
2010 張清堯(Ching-Yao Chang), Pd2(dba)3-promoted synthesis of 3-substituted 4-aryl-1,2,3,6-tetrahydropyridine, TETRAHEDRON LETTERS, vol.51 pp.4886-4889, 2010
2009 張清堯(Ching-Yao Chang)*, Efficient total syntheses of louisianins C and D, TETRAHEDRON, vol.65 no.4 pp.748-751, 2009
2009 張清堯(Ching-Yao Chang), Rhein induced apoptosis through the endoplasmic reticulum stress, caspase- and mitochondria-dependent pathways in SCC-4 human tongue squamous cancer cells, IN VIVO, vol.23 no.2 pp.309-316, 2009
2008 Aloe-emodin is an interferon-inducing agent with antiviral activity against Japanese encephalitis virus and enterovirus 71, INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, vol.32 pp.355-359, 2008
2007 Identification of a novel septin 4 protein binding to human herpesvirus 8 kaposin A protein using a phage display cDNA library, JOURNAL OF VIROLOGICAL METHODS, vol.143 pp.65-72, 2007
2007 Asymmetric zinc-Reformatsky reaction of Evans chiral imide with acetophenones and its application to the stereoselective synthesis of triazole antifungal agents, TETRAHEDRON-ASYMMETRY, vol.18 pp.949-962, 2007
2007 Practical synthesis of (-)-α-aminobenzolactam via nitration-cyclization of L-homophenylalanine ethyl ester, HETEROCYCLES, vol.71 pp.323-330, 2007
2007 Supercritical fluid extraction of imidazole drugs from cosmetic and pharmaceutical products, JOURNAL OF FOOD AND DRUG ANALYSIS, vol.15 no.1 pp.25-32, 2007
2006 Formal Synthesis of the ACE Inhibitor Benazepril HCl via an Asymmetric Aza-Michael Reaction, MOLECULES, vol.11 no.8 pp.641-648, 2006
2006 First total synthesis of louisianin A, JOURNAL OF ORGANIC CHEMISTRY, vol.71 pp.6302-6304, 2006
課程類別 課程代碼 課程名稱 年度
研究所博士班 EB100460A 生物技術專題講座(一) 111
大學日間部 TM300003A 普通化學 111
大學日間部 TM300081A 普通化學實驗 111
大學日間部 TM300081B 普通化學實驗 111
大學日間部 TM300127A 分析化學與儀器分析 111
大學日間部 TM300140A 訊息傳遞與藥物開發 111