张益铚 (Yi-Chih Chang)
状态 副教授
姓名 张益铚 (Yi-Chih Chang)
电子邮件 yichih@asia.edu.tw
职称 专任副教授
分机 04-23323456#20027
办公室/研究室 HB27
学历 国立中兴大学 兽医学系 博士
国立阳明大学 医学生物技术暨检验学系所 硕士
中国医药学院 医事技术学系 学士
元培医专 检验科
研究领域 临床微生物学、细胞诊断及组织病理学技术、临床镜检学、毒物检验学
教师历程档案 https://research.asia.edu.tw/TchEportfolio/index_1/107100154
Office Hours 110-2在校时间表
网站 http://mlsb.asia.edu.tw/files/13-1119-73665.php?Lang=zh-tw
专长 分子细菌学、临床细菌学、临床检验学、血液壆含实验、生物学、医学检验概论、微生物学含实验、免疫学、分子生物学、肿瘤生物学、应用微生物学、生物医学技术概论、医学伦理、遗传学
经历 亚洲大学 生物科技系 助理教授
中国医药大学 医学检验暨生物技术学系 助理教授
中台科技大学 医学检验生物技术学系 助理教授
中国医药大学 医学检验暨生物技术学系 讲师
中国医药学院 医事技术学系 助教
社团法人台中市长期照顾发展协会 学术顾问
社团法人南投县长期照顾发展协会 学术顾问
台中科技大学、逢甲大学、修平科技大学等校教师申诉评议委员会委员
年度 论文名称
2021 庄晓莉(Hsiao-Li Chuang)、张益铚(Yi-Chih Chang)、黄奕婷(Yi-Ting Huang)、廖君旺(Jiunn-Wang Liao)、高培玲(Pei-Ling Kao)、陈逸飞(Yi-Fei Chen)、林秉谊(Bin-Yin Lin)、林奕洛(Yi-Lo Lin)、陈德勋(Ter-Hsin Chen)、王裕智(Yu-Chih Wang)*, Establishment and Characterization of Feline Mammary Tumor Patient-Derived Xenograft Model, Animals, vol.11 pp.2380-
2021 Jan-Gowth Chang、田霓(Ni Tien)、张益铚(Yi-Chih Chang)、林孟亮(Meng-Liang Lin)、陈世顺(Shih-Shun Chen)*, Oxidative Stress-Induced Unscheduled CDK1-Cyclin B1 Activity Impairs ER-Mitochondria-Mediated Bioenergetic Metabolism, Cells, vol.10 pp.1280-
2019 张益铚(Yi-Chih Chang), Significance of sphingosine kinase 1 expressuon in feline mammary tumors., SOLAR ENERGY MATERIALS AND SOLAR CELLS
2019 张益铚(Yi-Chih Chang)、庄晓莉(Hsiao-Li Chuang3,)、Ji-Hang Yin、Jiunn-Wang Liao、陈德勋(Ter-Hsin Chen)、王裕智(Yu-Chih Wang)*, Significance of sphingosine kinase 1 expression in feline mammary tumors, BMC Veterinary Research, vol.15 no.1 pp.155-162
2017 张益铚(Yi-Chih Chang), Class 1 integrons and plasmid-mediated multiple resistance genes of the Campylobacter species from pediatric patient of a university hospital in Taiwan, Gut Pathogens
2017 张益铚(Yi-Chih Chang), Differences in Genetic Background Contribute to Pseudomonas Exotoxin A-Induced Hepatotoxicity in Rats, JOURNAL OF VENOMOUS ANIMALS AND TOXINS INCLUDING TROPICAL DISEASES
2017 张益铚(Yi-Chih Chang), TLR2 and interleukin-10 are involved in Bacteroides fragilis-mediated prevention of DSS-induced colitis in gnotobiotic mice., PLoS One
2017 张益铚(Yi-Chih Chang), Tubacin, an HDAC6 Selective Inhibitor, Reduces the Replication of the Japanese Encephalitis Virus via the Decrease of Viral RNA Synthesis, PLoS One
2017 张益铚(Yi-Chih Chang), Relationship of the CreBC two-component regulatory system and inner membrane protein CreD with swimming motility in Stenotrophomonas maltophilia, PLoS One
2016 张益铚(Yi-Chih Chang), Benzyl butyl phthalate promotes breast cancer stem cell expansion via SPHK1/S1P/S1PR3 signaling, OncoTargets and Therapy
2016 张益铚(Yi-Chih Chang), Comparison of the surface roughness of gypsum models constructed using various impression materials and gypsum products, Journal of Dental Sciences
2013 张益铚(Yi-Chih Chang), Association between hypertensive disorders during pregnancy and end-stage renal disease: a population-based study, CANADIAN MEDICAL ASSOCIATION JOURNAL
2012 张益铚(Yi-Chih Chang), Real-time PCR analysis of the intestinal microbiotas in peritoneal dialysis patients, APPLIED AND ENVIRONMENTAL MICROBIOLOGY
2012 张益铚(Yi-Chih Chang), Ameliorative Effects of Scopoletin from Crossostephium chinensis against Inflammation Pain and Its Mechanisms in Mice. Evid Based Complement Alternat Med, Evidence-based Complementary and Alternative Medicine
2012 张益铚(Yi-Chih Chang), Antiviral Activity of Isatis indigotica Extract and Its Derived Indirubin against Japanese Encephalitis Virus, Evidence-based Complementary and Alternative Medicine
2012 张益铚(Yi-Chih Chang), Risks, subtypes, and hospitalization costs of stroke among patients with systemic lupus erythematosus: a retrospective cohort study in Taiwan, SCANDINAVIAN JOURNAL OF RHEUMATOLOGY
2012 张益铚(Yi-Chih Chang), Bacteremia in hemodialysis and peritoneal dialysis patients, ANNALS OF INTERNAL MEDICINE
2011 张益铚(Yi-Chih Chang), Transmission of Salmonella between swine farms by the housefly (Musca domestica), JOURNAL OF FOOD PROTECTION
2011 张益铚(Yi-Chih Chang), SmQnrR, a DeoR-type transcriptional regulator, negatively regulates the expression of Smqnr and SmtcrA in Stenotrophomonas maltophilia, JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
2009 张益铚(Yi-Chih Chang), Characterization of the charge variants of L2 beta-lactamase in Stenotrophomonas maltophilia, JOURNAL OF MEDICAL MICROBIOLOGY
2009 张益铚(Yi-Chih Chang), Analysis of ciprofloxacin-resistant Salmonella strains from swine, chicken, and their carcasses in Taiwan and detection of parC resistance mutations by a mismatch amplification mutation assay PCR, JOURNAL OF FOOD PROTECTION
2006 张益铚(Yi-Chih Chang), Rapid detection and identification of clinically important bacteria by high-resolution melting analysis after broad-range ribosomal RNA real-time PCR, CLINICAL CHEMISTRY
2006 张益铚(Yi-Chih Chang), Construction and characterization of nisin-controlled expression vectors for use in Lactobacillus reuteri, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
年度 书名
2021 吴俊忠(Jiunn-Jong Wu)、张益铚(Yi-Chih Chang), 临床微生物学-细菌与霉菌学(第八版), 五南图书公司, 2021/10
2019 吴俊忠(Wu, Jiunn-Jong)、吴雪霞(Wu, Hsueh-Hsia)、周以正(Chou, Yii-Cheng)、周如文(Chou, Ru-wen)、胡文熙(Ho, Wen-si S)、洪贵香(Hong, Gui-xiang)、孙培伦(Sun, Pei-lun)、张长泉(Chang, Chang-Tsung)、张益铚(Yi-Chih Chang), 临床微生物学-细菌及霉菌学, 五南出版社出版。, 2019/10
发表日期 论文名称
2020.05 谢程丰(Cheng-Feng Hsieh)、田霓(Ni Tien)、许玉龙(Yu-Lung Hsu)、邓志敦(Chih-Tun Teng)、林冠语(Kuan-Yu Lin)、林君黛(Lin, Jun-Dai)、张益铚(Yi-Chih Chang), Analysis the antimicrobial susceptibility of Clostridium difficile from university hospital at the western area of Taiwan. , 2020 Joint Biotechnology Conference of China Medical University and Asia University, Taiwan, Taichung,China Medical University
2019.05 陈雅玲(Chen, Ya-ling)、林君黛(Lin, Jun-Dai)、陈丽丽(Chen, Li-Li)、吴珮瑜(Wu, Ju-yu)、张益铚(Yi-Chih Chang)、林冠语(Kuan-Yu Lin), 国中青少女原发性痛经与中医体质相关性研究 , 2019玉山研讨会., 台湾,台中,中台科技大学
2019.05 方诘恺(Jie-Kai Fang)、张益铚(Yi-Chih Chang), Analysis the adhesive virulence genes (cadF, flaA and racR genes) in Campylobacter species isolates from human and animal specimens. , 2019 Joint Biotechnology Conference of China Medical University and Asia University., Taiwan/Taichung/Asia University
2019.05 许楷翔( Kai-Hsiang Hsu)、张益铚(Yi-Chih Chang), Detection of tetracycline resistance genes in Campylobacter species isolates from human, chicken and swine specimens. , 2019 Joint Biotechnology Conference of Asia University and China Medical University., Taiwan/Taichung/Asia University
2019.04 邓志敦(Chih-Tun Teng), An Experience Sharing of Optimizing Laboratory Management Process , Using SharePoint into Management Department Process as an Example. - 11th Asia-Pacific Forum of Medical Laboratory Sciences, Chung Shan Medical University, Taichung
2019.04 邓志敦(Chih-Tun Teng)、张昱伟(Yu-Wei Chang)、赖小婷(Hsiao-Ting Lai)、林贞(Chen Lin)、陈昱衡(Yu-Heng Chen)、张益铚(Yi-Chih Chang), 11th Asia-Pacific Forum of Medical Laboratory Sciences 2019., Taiwan, Taichung, Chung Shan Medical University, Taichung
2018.11 Hsiang-Te Tsai、张益铚(Yi-Chih Chang), 台湾西部地区猪只肠道乳酸杆菌耐酸碱特性分析(Analysis the acid tolerance and bile salts hydrolysis of Lactobacillus species from swine intestinal specimens at the western area of Taiwan) , 台湾微生物学会第二十二届第三次会员大会暨学术研讨会, 台湾台北台湾大学医学院
2018.11 林妍伶(Yan-Ling Lin)、张益铚(Yi-Chih Chang), 侦测在人类、鸡和猪只检体中弯曲杆菌侵袭毒力基因的分析表现(Detection the invasion virulence genes (ciaB, iam, pldA, and virBll genes) in Campylobacter species isolates from human, chicken and swine specimens) , 台湾微生物学会第二十二届第三次会员大会暨学术研讨会, 台湾台北 台湾大学医学院101,102讲堂
2018.11 兴仁杰(Ren-Jay Shing)、张益铚(Yi-Chih Chang), Analysis of erythromycin reisitance genes in Campylobacter species isolates from human, chicken and swine specimens , 107年度医检学会年度大会学术研讨会, 台湾台北台大医院国际会议中心
2018.05 林昭岑(Chao-Tsen Lin)、张益铚(Yi-Chih Chang)、邓志敦( Chih-Tun Teng), 14. Analysis the antimicrobial susceptibility test of Gram, Negative Bacilli by VITEK 2 system in Taitung Christian Hospital, Taitung - 2018年中国医药大学暨亚洲大学生物科技研讨会, 台湾台中中国医药大学B1国际会议厅
2018.05 林昭岑(Chao-Tsen Lin)、张益铚(Yi-Chih Chang)、邓志敦(Chih-Tun Teng), 13. The antimicrobial susceptibility test of Stapylococcus aureus and beta, hemolytic streptococci by VITEK 2 system at east area of Taiwan - 2018年中国医药大学暨亚洲大学生物科技研讨会, 台湾台中中国医药大学B1国际会议厅
2018.05 罗凯腾(Kai-Teng Lo)、张益铚(Yi-Chih Chang), Detection the major virulence genes (cytolethal distending toxin genes) in Campylobacter species isolates from human, chicken and swine specimens , 2018年中国医药大学暨亚洲大学生物科技研讨会, 台湾台中中国医药大学B1国际会议厅
2016.11 陈弘翰(Hong-Han Chen)、张益铚(Yi-Chih Chang), Analysis the patterm of gene cassette arrays in class I integron from clinical Acinetobacter baumanni isolates at central area of Taiwan , 台湾医检杂志 (105年度年会大会), 台湾台北国际会议中心
2016.11 吴柏宽(Bo-Kuan Wu)、张益铚(Yi-Chih Chang), Molecular characterization of Campylobacter species isolated from pediatric gastroenteritis patients at central area of Taiwan , 台湾医检杂志 (105年度年会大会), 台湾台北国际会议中心
2016.03 蔡相德(Hsiang-Te Tsai)、张益铚(Yi-Chih Chang), Analysis of class I Integron from multiple drug resistance Acinetobacter baumanni in clinical isolates , 第九届中国医药大学暨亚洲大学生物科技研讨会, 中国医药大学立夫教学大楼B1国际会议厅
2016.03 万宗函(Tsung-Han Wan)、张益铚(Yi-Chih Chang), Antimicrobial susceptibility of Hsu, 48 drug against the emergence of antimicrobial resistance beta-hemolytic streptococci in clinical isolates - 第九届中国医药大学暨亚洲大学生物科技研讨会, 台湾台中中国医药大学立夫教学大楼B1国际会议厅
2016.03 田霓(Ni Tien)、张益铚(Yi-Chih Chang), Antimicrobial activity of synthetic analogues (Hsu, 48 drug) against the emergence of antimicrobial resistance MRSA and coagulase-negative Staphylococci - 第九届中国医药大学暨亚洲大学生物科技研讨会, 台湾台中中国医药大学立夫教学大楼B1国际会议厅
2015.10 田霓(Ni Tien)、张益铚(Yi-Chih Chang), Antimicrobial activity of Hsu, 48 drug (a new nordihydroguaiaretic acid derivative) in clinical pathogens - 台湾微生物学会第二十一届第三次台湾微生物学会年会暨会员大会, 台湾台北国际会议中心
2014.10 曾焕鸿(Huan-Hung Tseng)、张益铚(Yi-Chih Chang)、吴怡莹(YI-YING Wu), NC, 8 inhibits RANK ligand induced osteoclast differentiation from Monocyte/ Macrophages Lineage precursor cell - 2014年中华民国免疫学会会员大会暨学术演讲会, 台湾台湾大学医学院一楼102、103、104讲堂
2013.11 王怡宽, Antimicrobial susceptibility of vanillin against several Lactobacillus species isolated from swine guts at the western area of Taiwan. , 「益生菌及代谢物之多重应用」学术与产业应用研讨会暨台湾乳酸菌协会第五届第二次会员大会, 台湾大学凝态物理馆2F国际会议厅
2013.11 王怡宽, Antimicrobial activity of vanillin against lactic acid bacteria isolated from indigenous children feces at the western area of Taiwan. , 「益生菌及代谢物之多重应用」学术与产业应用研讨会暨台湾乳酸菌协会第五届第二次会员大会, 台湾大学凝态物理馆2F国际会议厅
2013.08 王怡宽, Antimicrobial activity of vanillin to the emergence of antimicrobial resistance pathogens in clinical isolates. , 第18届细菌学研讨会, 惠荪实验林场
2013.03 邓宛蓉, 中草药木通诱发单核球/巨噬细胞的前驱细胞分化成为蚀骨细胞 , 第六届亚洲大学与中国医药大学两校合作学术研讨会, 亚洲大学行政大楼一楼哈佛讲堂、管理大楼地下一楼
2010.03 林怡婷, Lactobacillus can suppress the apoptosis that caused by Helicobacter pylori infection , 第三届亚洲大学及中国医药大学生物技术联合研讨会, 亚洲大学
2009.02 许振婷, 幽门螺旋杆菌胃炎病人会增加趋化激素CCL20的表现量并召集CCR6+胃浸润T细胞 , 2009研究学习群日月潭校级研究成果发表会, 日月潭
2009.02 许振婷, 14. Upregulation of CCL20 and Recruitment of CCR6 Gastric Infiltrating Lymphocytes in Helicobacter pylori Gastritis , 97年度中国医药大学P3-4研究学习群之推广, 2009研究学习群校级研究成果发表会, 日月潭教师会馆
2008.12 张益铚(Yi-Chih Chang), Distribution of tet genes and antimicrobial susceptibility of several Lactobacillus species isolated from swine guts at the western area of Taiwan. , 发酵乳的无可取代价值」学术研讨会暨台湾乳酸菌协会第三届第一次会员大会, 弘光科技大学生活应用大楼国际会议厅
2008.06 Y-C. Wang, Antimicrobial Resistance and Genetic Relatedness among Salmonella Schwarzengrund from Slaughtering Broiler and Human. , The 108th General Meeting of the American Society for Microbiology, Boston, MA, USA.
2008.06 张益铚(Yi-Chih Chang), The AmpR Protein Regulates the L1 β, Lactamase Expression in Stenotrophomonas maltophilia - The 108th General Meeting of the American Society for Microbiology, Boston, MA, USA.
2008.06 T-H. Chen, Investigation of Salmonella Infection in Household and Stray Dogs of Central Taiwan , The 108th General Meeting of the American Society for Microbiology, Boston, MA, USA.
2007.12 张益铚(Yi-Chih Chang), Antimicrobial activity of cultural secretions from probiotics Lactobacillus acidophilus against some antibiotic, resistant pathogens isolated from pediatric populations. - 台湾微生物学会第四十周年庆会员大会学术研讨会, 台北市台大医院国际会议中心
2007.07 Yu-Chih Wang, Rapid detection of fluoroquinolone, resistant Salmonella by Multiplex Allele specific PCR - 第三届沙门氏菌暨其他细菌人畜共通疾病研讨会, 台中市 , 中兴大学兽医学院
2006.11 张益铚(Yi-Chih Chang), Characterization of anti, bacterial and cholesterol-lowering function for Enterococcus faecium 57a-1, 58a-1, and 63b-2 - 台湾乳酸菌协会2006年年度大会暨学术研讨会, 台北市 , 台湾大学凝态科学暨物理学馆国际会议厅(二楼204室)
2006.11 张益铚(Yi-Chih Chang), Distribution of tetracycline resistant genes in lactic acid bacteria isolated from human feces and swine guts in Taiwan , 台湾乳酸菌协会2006年年度大会暨学术研讨会, 台北市 , 台湾大学凝态科学暨物理学馆国际会议厅(二楼204室)
计画名称 参与人 计画期间
猫乳腺瘤外泌体SPHK1与肝转移前微环境建立 ((110-2313-B-005-047-)) 王裕智(Yu-Chih Wang) 2021.08 ~ 2022.07
奖项名称 颁奖单位
Antimicrobial susceptibility of cefoxitin and penicillin G against the emergence of clinical Clostridium difficile isolates Taiwan Lactic Acid Bacteria Association.
课程类别 课程代码 课程名称 年度
大学日间部 TM300150A 学辅时间(四) 111
大学日间部 GOG00447A 动物与生活-4 111
进修学士班 BRG00034A 健康与生活 111
年分 计画名称 指导教授 学系 学生姓名
109 以肿瘤外泌体做为抗癌药物载体之研究分析 张益铚 医学检验暨生物技术学系 陈立恩
108 舞菇萃取物在成骨细胞与破骨细胞之分化研究 张益铚 生物科技系 吴明和