张清尧 (Ching-Yao Chang)
姓名 张清尧 (Ching-Yao Chang)
职称 专任教授
学历 国立中兴大学化学 博士
中州技术学院 通识教育中心
朝阳科技大学 应用化学系
分机 04-23323456#1863
办公室/研究室 I421/H407
研究领域 普通化学、有机化学
专长 普通化学、有机化学
年度 论文名称
2023 Chih-Sheng Chen(Chih-Sheng Chen)*、张清尧(Ching-Yao Chang), Acupuncture modulates development of myopia by reducing NLRP3 inflammasome activation via the dopamine-D1R signaling pathway, Acupuncture in Medicine pp.1-12, 2023
2022 Yao-Chien Wang、万磊(Lei Wan)*, In vivo and in vitro evidence for growth hormone-like bioactivity of Rhizoma Anemarrhenae extract, BIOMEDICINE & PHARMACOTHERAPY, vol.153 pp.113489-113496, 2022
2022 Chih-Sheng Chen,、万磊(Lei Wan)*, Fallopia Japonica and Prunella vulgaris inhibit myopia progression by suppressing AKT and NFκB mediated inflammatory reactions, BMC Complementary Medicine and Therapies, vol.22 pp.271-284, 2022
2021 Yu-An Hsu、张清尧(Ching-Yao Chang), Anti-Inflammatory Effects of Resveratrol on Human Retinal Pigment Cells and a Myopia Animal Model, CURRENT ISSUES IN MOLECULAR BIOLOGY, vol.43 pp.716-727, 2021
2021 Peng-Tai Tien、Chia-Hung Lin(Chia-Hung Lin)*、张清尧(Ching-Yao Chang), Diacerein Inhibits Myopia Progression through Lowering Inflammation in Retinal Pigment Epithelial Cell, MEDIATORS OF INFLAMMATION, vol.2021 no.6660640 pp.1-11, 2021
2020 张清尧(Ching-Yao Chang)、万磊(Lei Wan)*, Amelioration of bleomycin-induced pulmonary fibrosis via TGF-β-induced Smad and non-Smad signaling pathways in galectin-9-deficient mice and fibroblast cells, JOURNAL OF BIOMEDICAL SCIENCE, vol.27 no.24 pp.1-9, 2020
2020 En-Shyh Lin、张清尧(Ching-Yao Chang)、万磊(Lei Wan)*, Ablation of Galectin-12 Inhibits Atherosclerosis through Enhancement of M2 Macrophage Polarization, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol.21 no.15 pp.5511-5524, 2020
2020 Peng?Tai Tien、张清尧(Ching-Yao Chang), Perfluorooctanoic acid in indoor particulate matter triggers oxidative stress and inflammation in corneal and retinal cells, Scientific Reports, vol.1 no.10 pp.15702-15713, 2020
2019 Chang-Ching Wei、张清尧(Ching-Yao Chang)、万磊*, PM2.5 and NOx exposure promote myopia: clinical evidence and experimental proof, ENVIRONMENTAL POLLUTION, vol.254 pp.113031-113038, 2019
2018 魏长菁(Chang-Ching Wei)、万磊*、, Allergic Conjunctivitis-induced Retinal Inflammation Promotes Myopia Progression, EBioMedicine, 2018
2018 Chia-Wen Lo、万磊*、, Allyl isothiocyanate ameliorates obesity by inhibiting galectin-12, MOLECULAR NUTRITION & FOOD RESEARCH, 2018
2018 Yu-An Hsu、张清尧(Ching-Yao Chang)、万磊*, Galectin-12 is Involved in Corn Silk-Induced Anti-Adipogenesis and Anti-Obesity Effects, The American journal of Chinese medicine, vol.46 no.5 pp.1-19, 2018
2018 万磊*、张清尧, The synergistic effects of orthokeratology and atropine in slowing the progression of myopia, Journal of clinical medicine, vol.7 no.9 pp.259-267, 2018
2017 Yung-Jen Kun、、万磊*、、, Kawasaki disease increases the incidence of myopia, Biomed Research International, 2017
2016 Lin, H.-J.、万磊*, Role of Chronic Inflammation in Myopia Progression: Clinical Evidence and Experimental Validation, EBioMedicine, vol.10 pp.269-281, 2016
2016 万磊*、张清尧(Ching-Yao Chang), Galectin-12 enhances inflammation by promoting M1 polarization of macrophages and reduces insulin sensitivity in adipocytes, GLYCOBIOLOGY, vol.26 pp.732-744, 2016
2016 Lin, C.-H.、万磊*, Cold-water extracts of Grifola frondosa and its purified active fraction inhibit hepatocellular carcinoma in vitro and in vivo, EXPERIMENTAL BIOLOGY AND MEDICINE, vol.241 no.13 pp.1374-1385, 2016
2016 Hsu, Yu-An、张清尧(Ching-Yao Chang)、万磊*, The anti-proliferative effects of type I IFN involve STAT6-mediated regulation of SP1 and BCL6, CANCER LETTERS, vol.375 pp.303-312, 2016
2015 张清尧(Ching-Yao Chang)、万磊*, MUTYH Gene Polymorphisms as Risk Factors for Rheumatoid Arthritis, BioMed Research International, vol.2015 pp.1-8, 2015
2015 张清尧(Ching-Yao Chang)、万磊*, Flavones inhibit breast cancer proliferation through the Akt/FOXO3a signaling pathway, BMC CANCER, vol.15 no.958 pp.1-12, 2015
2014 张清尧(Ching-Yao Chang), Structurally well-characterized zinc complexes bearing iminebenzotriazole phenoxide ligands: Synthesis, photoluminescent properties and catalysis for carbon dioxide/epoxide coupling, Journal of Organometallic Chemistry, vol.754 pp.16-25, 2014
2014 张清尧(Ching-Yao Chang)*, An Efficient Synthesis of the C27-C45 Fragment of Lagunamide A, a Cyclodepsipeptide with Potent Cytotoxic and Antimalarial Properties, TETRAHEDRON-ASYMMETRY, vol.25 no.2 pp.187-192, 2014
2014 张清尧(Ching-Yao Chang)、万磊(Lei Wan)*, [PDF] Association of Interleukin-16 Polymorphisms with Graves' Disease in a Taiwanese Population, CHINESE JOURNAL OF PHYSIOLOGY, vol.57 no.2 pp.69-75, 2014
2013 黄素华(Su-Hua Huang)、张清尧(Ching-Yao Chang), Baicalein, Ethyl Acetate, and Chloroform Extracts of Scutellaria baicalensis Inhibit the Neuraminidase Activity of Pandemic 2009 H1N1 and Seasonal Influenza A Viruses, Evidence-based Complementary and Alternative Medicine, vol.2013 pp.1-11, 2013
2013 张清尧(Ching-Yao Chang)、万磊(Lei Wan)*, Genetic variation in NOS2A is associated with a sustained virological response to peginterferon plus ribavirin therapy for chronic hepatitis C in Taiwanese Chinese, JOURNAL OF MEDICAL VIROLOGY, vol.85 no.7 pp.1206-1214, 2013
2012 张清尧(Ching-Yao Chang), Determination of trace indium in urine after preconcentration with a chelating resin-packed minicolumn, JOURNAL OF SEPARATION SCIENCE, vol.35 no.7 pp.846-852, 2012
2012 张清尧(Ching-Yao Chang)、林振文(CHENG-WEN LIN), Rhein Induces Apoptosis in Human Breast Cancer Cells, Evidence-based Complementary and Alternative Medicine, vol.2012 pp.1-8, 2012
2011 赖淑玲(Shu Ling Lai), (4Z)-4-[(2,6-Diisopropylanilino)(phenyl)methylidene]- 3-methy-1-phenyl-1H-pyrazol-5(4H)-one, ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, vol.E67 pp.o324-, 2011
2011 张清尧(Ching-Yao Chang), Efficient synthesis of the C1-C9 fragment of 7,8-O-isopropylidene protected iriomoteolide 3a derivative, JOURNAL OF THE CHINESE CHEMICAL SOCIETY, vol.58 no.1 pp.31-34, 2011
2011 张清尧(Ching-Yao Chang), A Short and Efficient Synthesis of a Novel Diarylheptanoid Isolated from Pleuranthodium Racemigerum, JOURNAL OF THE CHINESE CHEMICAL SOCIETY, vol.58 no.3 pp.286-289, 2011
2010 张清尧(Ching-Yao Chang), BF3-promoted synthesis of diarylhexahydrobenzo[f]isoquinoline, ORGANIC LETTERS, vol.12 pp.1176-1179, 2010
2010 张清尧(Ching-Yao Chang), Solannm lyratum extract affected immune response in normal and leukemia murine animal in vivo, HUMAN & EXPERIMENTAL TOXICOLOGY, vol.29 no.1 pp.359-367, 2010
2010 张清尧(Ching-Yao Chang), BF3-promoted synthesis of spiroindenyl heterocycles, TETRAHEDRON LETTERS, vol.51 pp.3154-3158, 2010
2010 许成光(Cheng-Kuang Hsu)、王建国(Chien-Kuo Wang)、张清尧(Ching-Yao Chang), Solanum lyratum extract inhibits Helicobacter pylori-mediated apoptosis in human gastric epithelial cells, ANTICANCER RESEARCH, vol.30 pp.1189-1194, 2010
2010 张清尧(Ching-Yao Chang), Pd2(dba)3-promoted synthesis of 3-substituted 4-aryl-1,2,3,6-tetrahydropyridine, TETRAHEDRON LETTERS, vol.51 pp.4886-4889, 2010
2009 张清尧(Ching-Yao Chang)*, Efficient total syntheses of louisianins C and D, TETRAHEDRON, vol.65 no.4 pp.748-751, 2009
2009 张清尧(Ching-Yao Chang), Rhein induced apoptosis through the endoplasmic reticulum stress, caspase- and mitochondria-dependent pathways in SCC-4 human tongue squamous cancer cells, IN VIVO, vol.23 no.2 pp.309-316, 2009
2008 Aloe-emodin is an interferon-inducing agent with antiviral activity against Japanese encephalitis virus and enterovirus 71, INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, vol.32 pp.355-359, 2008
2007 Identification of a novel septin 4 protein binding to human herpesvirus 8 kaposin A protein using a phage display cDNA library, JOURNAL OF VIROLOGICAL METHODS, vol.143 pp.65-72, 2007
2007 Asymmetric zinc-Reformatsky reaction of Evans chiral imide with acetophenones and its application to the stereoselective synthesis of triazole antifungal agents, TETRAHEDRON-ASYMMETRY, vol.18 pp.949-962, 2007
2007 Practical synthesis of (-)-α-aminobenzolactam via nitration-cyclization of L-homophenylalanine ethyl ester, HETEROCYCLES, vol.71 pp.323-330, 2007
2007 Supercritical fluid extraction of imidazole drugs from cosmetic and pharmaceutical products, JOURNAL OF FOOD AND DRUG ANALYSIS, vol.15 no.1 pp.25-32, 2007
2006 Formal Synthesis of the ACE Inhibitor Benazepril HCl via an Asymmetric Aza-Michael Reaction, MOLECULES, vol.11 no.8 pp.641-648, 2006
2006 First total synthesis of louisianin A, JOURNAL OF ORGANIC CHEMISTRY, vol.71 pp.6302-6304, 2006
年度 书名
2015 张清尧(Ching-Yao Chang)、刘惠铭、陈明仁、杨雅甄(Ya-Chen Yang)、张竣维(Hebron C. Chang), 有机化学, 东华书局, Jun. 2015
2014 普通化学, 高立图书, Jan. 2014
计画名称 参与人 计画期间
具高度细胞毒性之生物分子lagunamide A和B的合成研究 (NSC 100-2113-M-468-001) 2011.08 ~ 2012.07
具高度细胞毒性之大环分子iriomoteolide-3a及其7,8-O-异丙基衍生物的合成研究 (99-2113-M-468-001) 张清尧(Ching-Yao Chang) 2010.07 ~ 2011.07
脂质代谢活性促进剂—双帖类生物碱Nigellamines及其衍生物的合成研究 (96-2113-M-468-001) 张清尧(Ching-Yao Chang) 2007.08 ~ 2008.07
单萜类生物碱(-)-oxerine的不对称合成 (95-2113-M-468-001) 张清尧(Ching-Yao Chang) 2006.08 ~ 2007.07
SC 115细胞抑制剂-Louisianin A的合成(2/2) (94-2113-M-468-002) 张清尧(Ching-Yao Chang) 2005.08 ~ 2006.07
SC 115细胞抑制剂-Louisianin A的合成(1/2) (94-2113-M-468-001) 张清尧(Ching-Yao Chang) 2005.01 ~ 2004.07
课程类别 课程代码 课程名称 年度
大学日间部 TM300003A 普通化学 113
大学日间部 TM300003B 普通化学 113
大学日间部 TM300062A 医学分子检验实习 113
大学日间部 TM300081A 普通化学实验 113
大学日间部 TM300081B 普通化学实验 113
大学日间部 TM300127A 分析化学与仪器分析 113
大学日间部 TM300127B 分析化学与仪器分析 113
大学日间部 TM300148A 学辅时间(二) 113
大学日间部 TM300148A 学辅时间(二) 113